Cat: IPD-X38461

Recombinant Human COL16 Protein,His

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关键信息

  • 基因名

    COL16

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    COL16A1; COL16-A1; Collagen Alpha-1(XVI)chain

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q07092

  • 表达区间

    Val1434~Gly1604

  • 分子量

    23kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

Collagen type XVI (COL16) is a crucial component of the extracellular matrix, primarily found in various tissues such as skin, tendon, and vascular systems. It belongs to the class of fibril-forming collagens and plays a vital role in tissue structure and function. Research on COL16 has drawn attention due to its involvement in multiple physiological processes, including cell adhesion, migration, and proliferation, as well as its implications in several pathological conditions, such as fibrosis, cancer, and wound healing. The study of recombinant COL16 protein has gained momentum as it provides a promising tool for understanding the molecular mechanisms underlying these biological functions. By producing COL16 in a recombinant form, researchers can investigate its specific roles in cell signaling pathways, interactions with other extracellular matrix components, and its effects on cellular behavior. Furthermore, recombinant COL16 is invaluable in developing biomaterials for tissue engineering and regenerative medicine, where it can aid in creating scaffolds that mimic native tissue environments. This research is essential for potential therapeutic interventions and improving outcomes in conditions where COL16 is implicated. Overall, the exploration of COL16 and its recombinant forms opens new avenues for advancing our understanding of collagen biology and its applications in medicine.

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