关键信息
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基因名
VGLUT1
- 应用
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别名
SLC17A7; BNPI; Solute Carrier Family 17 Member 7,Sodium-Dependent Inorganic Phosphate Cotransporter; Brain-specific Na(+)-dependent inorganic phosphate cotransporter
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q3TXX4
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表达区间
Ser491~Tyr560
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分子量
30kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
VGLUT1 (Vesicular Glutamate Transporter 1) plays a crucial role in the regulation of glutamate, the primary excitatory neurotransmitter in the central nervous system. By facilitating the packaging of glutamate into synaptic vesicles, VGLUT1 is essential for synaptic transmission and neuronal communication. Dysregulation of glutamate signaling is implicated in various neuropsychiatric disorders, such as schizophrenia, autism, and epilepsy, making VGLUT1 a significant focus of research. The study of VGLUT1 recombinant protein has emerged as a vital approach to deepen our understanding of its functional mechanisms, regulation, and interaction with other proteins. Utilizing recombinant DNA technology, researchers can produce VGLUT1 in controlled laboratory conditions, allowing for detailed analysis of its structural and functional properties. Additionally, understanding the molecular dynamics of VGLUT1 can provide insights into potential therapeutic strategies aimed at modulating glutamatergic signaling, ultimately contributing to the development of treatments for disorders associated with glutamate dysregulation. As research advances, the characterization of VGLUT1 recombinant protein continues to shed light on its significance in neuronal function and overall brain health, highlighting its potential as a target for pharmacological intervention.
