关键信息
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基因名
EDN2
- 应用
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别名
ET2; PPET2; Preproendothelin-2
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P20800
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表达区间
Gln32~Arg178
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分子量
21kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
EDN2, or Endothelin-2, is a critical peptide belonging to the endothelin family, known for its potent vasoconstrictive properties and roles in various physiological processes, such as angiogenesis and cellular proliferation. Originally identified as a product of endothelial cells, EDN2 has garnered attention due to its involvement in pathological conditions, including cardiovascular diseases, cancer, and pulmonary disorders. Research has demonstrated that EDN2 can influence cell signaling pathways through its interaction with endothelin receptors, leading to diverse biological effects that are significant in both health and disease. Moreover, advancements in recombinant protein technologies have enabled the production of EDN2 for further functional studies, facilitating the exploration of its mechanisms in cellular environments. Investigating EDN2's role in disease conditions offers potential therapeutic insights and targets, making it an important focus within the fields of molecular biology and pharmacology. Understanding the biological functions and regulatory mechanisms of EDN2 is crucial for developing innovative strategies for disease intervention and improving patient outcomes. Furthermore, studies on EDN2's interactions at the molecular level can enhance our comprehension of endothelial biology and its implications in various pathological states.
