关键信息
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基因名
SEPT5
- 应用
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别名
CDCREL; CDCREL-1; CDCREL1; H5; PNUTL1; Peanut-Like 1; Cell division control-related protein 1
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99719
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表达区间
Ser77~Ser323
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分子量
30kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
SEPT5, also known as Septin 5, is a member of the septin family of GTP-binding proteins that play crucial roles in various cellular processes, including cell division, cytoskeletal organization, and vesicle trafficking. This protein is particularly interesting due to its involvement in the formation of septin complexes, which are thought to function as scaffolding components in the assembly of cellular structures. Research has shown that SEPT5 is implicated in several physiological processes, such as cell cycle regulation and neuronal function, and has been linked to various diseases, including cancer and neurodegenerative disorders. The study of SEPT5 has gained momentum in recent years as scientists explore its role in disease mechanisms and potential as a therapeutic target. Investigating the structure and function of SEPT5, particularly in the context of its interactions with other cellular proteins and its regulatory mechanisms, is crucial for understanding its biological significance. Advancements in techniques such as X-ray crystallography and cryo-electron microscopy have enabled researchers to elucidate the molecular details of SEPT5, paving the way for novel therapeutic strategies targeting septin-associated pathways. Furthermore, the modulation of SEPT5 activity is being explored for its potential to influence tumorigenesis and neurodegenerative processes, making it a focal point for future research in cellular biology and medicine.
