Cat: IPD-X39586

Recombinant Human TMC5 Protein,His

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关键信息

  • 基因名

    TMC5

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q6UXY8

  • 表达区间

    Met1~Ala210

  • 分子量

    30kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

TMC5, or Transmembrane Channel-like 5, is a protein that plays a crucial role in cellular processes, particularly in the context of viral infections and immune responses. Recent studies have highlighted its significant involvement in the life cycle of various viruses, including its potential role as a receptor facilitating viral entry into host cells. The interest in TMC5 has surged due to its dual functions, both as a channel involved in ion transport and as a mediator in cellular signaling pathways. Understanding the mechanisms by which TMC5 interacts with viral components may provide insights into the development of novel therapeutic strategies against viral diseases. The recombinant expression of TMC5 in various systems allows researchers to study its structural properties and functional characteristics in detail. Additionally, investigations into post-translational modifications and interactions with other cellular proteins are essential for deciphering its role in pathophysiological contexts. The mounting evidence concerning its implications in immune evasion and host-pathogen interactions frames TMC5 as a pivotal target for drug discovery and vaccine development. As such, research on TMC5 recombinant protein not only enhances our understanding of its biological significance but also opens new avenues for combating viral infections, making it a focal point of current molecular biology and virology studies.

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