关键信息
-
基因名
KRT28
- 应用
-
别名
KRT25D; K28; K25D; Cytokeratin-28; Type I inner root sheath-specific keratin-K25irs4; Keratin, type I cytoskeletal 28
-
种属
Mouse
-
表达系统
E. coli
-
标签
N- His & GST
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
A6BLY7
-
表达区间
Met1~Phe462
-
分子量
80kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
KRT28, also known as Keratin 28, is a member of the keratin family of proteins that play crucial roles in the structural integrity and function of epithelial tissues. Keratins are essential components of the cytoskeleton in various cells, particularly in skin, hair, and nails, providing mechanical resilience and protection against physical and chemical stress. Research on KRT28 has gained increasing attention due to its potential involvement in skin disorders and cancers. Studies have indicated that abnormalities in keratin expression, including KRT28, may be linked to pathological states such as keratinocyte differentiation issues, inflammatory skin diseases, and tumor progression. Consequently, understanding the molecular mechanisms governing KRT28 expression and function can provide insights into its role in skin biology and disease. Additionally, the reconstitution and characterization of KRT28 as a recombinant protein may facilitate the exploration of its biochemical properties, interactions with other cellular components, and its potential applications in regenerative medicine and therapeutic strategies for skin-related conditions. Overall, KRT28 serves as a significant focus in dermatological research, bridging the gap between basic keratin biology and clinical implications.
