关键信息
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基因名
EYA2
- 应用
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别名
EAB 1; EAB1; EYA 2; EYA transcriptional coactivator and phosphatase 2; EYA2; EYA2_HUMAN; eyes absent 2 homolog (Drosophila); Eyes absent homolog 2 (Drosophila); Eyes absent homolog 2; Translation of this uORF probably lowers the translation efficiency of EYA2
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O00167
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表达区间
1-514aa
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分子量
72.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
EYA2, a member of the Eyes Absent (EYA) protein family, plays a significant role in various developmental processes and cell signaling pathways. This group of proteins is known for its involvement in the regulation of gene expression and the formation of specific tissues and organs during embryonic development. EYA2 is particularly essential in the development of the eye, kidney, and other organs, acting as a transcriptional co-activator that interacts with other key regulatory proteins. Research has increasingly focused on EYA2 due to its potential implications in various diseases, including cancer and congenital disorders. The recombinant protein version of EYA2 has become a valuable tool for dissecting its functional roles in cellular mechanisms and for understanding the molecular underpinnings of its associated pathologies. By producing recombinant EYA2, researchers aim to investigate its biochemical properties, binding interactions, and regulatory functions in cellular environments. This study is crucial for elucidating the pathways through which EYA2 operates and could lead to developments in targeted therapeutic strategies for diseases linked to EYA2 dysregulation. Overall, the exploration of EYA2 recombinant protein embodies a promising frontier in developmental biology and medical research, providing insights that could pave the way for innovative treatments and interventions.
