关键信息
-
基因名
RAP2B
- 应用
-
别名
MGC20484; RAP 2B; RAP2A; Rap2b; RAP2B member of RAS oncogene family; RAP2B_HUMAN; Ras family small GTP binding protein RAP2B; Ras related protein RAP 2B; Ras related protein RAP2B; Ras-related protein Rap-2b; Small GTP binding protein
-
种属
Human
-
表达系统
E. coli
-
标签
N- GST
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P61225
-
表达区间
1-183aa
-
分子量
47.2 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
RAP2B (Ras-related protein 2B) is a member of the Ras superfamily of GTPases, which are crucial regulators of diverse cellular processes, including growth, differentiation, and vesicle trafficking. It has been implicated in various physiological functions and pathological conditions, such as cancer and cardiovascular diseases. The study of RAP2B, especially through the production of recombinant protein, allows researchers to investigate its structure-function relationships and interaction with effector proteins. Recombinant RAP2B can be used to elucidate the mechanisms by which it regulates cellular signaling pathways and its role in disease progression. Furthermore, the development of RAP2B as a therapeutic target requires an in-depth understanding of its biological functions, making the production and characterization of this protein vital for advancing molecular biology and potential therapeutic interventions. By utilizing techniques such as molecular cloning and protein expression systems, researchers can produce active RAP2B, thereby facilitating the study of its biochemical properties, interaction with other cellular proteins, and impact on various signaling cascades. This recombinant protein approach not only enhances our understanding of RAP2B's role in normal physiology but also its aberrations in disease states, contributing to the broader field of cancer research and targeted therapies.
