关键信息
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基因名
LCE2C
- 应用
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别名
LCE2C; LEP11Late cornified envelope protein 2C; Late envelope protein 11
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5TA81
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表达区间
1-110aa
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氨基酸序列
MSCQQNQQQCQPPPKCPPKCTPKCPPKCPPKCPPQCPAPCFPAVSSCCGPSSGSCCGPSSGGCCSSGAGGCSLSHHRPRLFHRRRHQSPDCCESEPSGGSGCCHSSGGCC
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分子量
12.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
LCE2C (Late Cornified Envelope 2C) is a gene belonging to the LCE family, which plays a pivotal role in the formation of the skin barrier and in the regulation of epidermal differentiation. Research into LCE2C is particularly significant due to its implications in skin-related disorders, including psoriasis, dermatitis, and other keratinization disorders. The expression of LCE2C is regulated by various factors, including cytokines and environmental stressors, making it crucial for understanding the adaptive mechanisms of skin under pathological conditions. Given its role in keratinocyte function and the overall integrity of the skin barrier, LCE2C is considered a promising target for therapeutic interventions in skin diseases. Furthermore, the recombinant expression of LCE2C can facilitate the exploration of its functional properties and interactions within the epidermis. By producing LCE2C as a recombinant protein, researchers can conduct detailed studies on its biochemical properties, structural characteristics, and potential interactions with other proteins, thus enhancing our understanding of its biological functions. This knowledge can pave the way for innovative treatments and diagnostic tools in dermatology, fundamentally contributing to skin health and disease management. The investigation of LCE2C and its potential applications has emerged as a critical area of research aimed at elucidating the complex mechanisms of skin biology and therapy.
