关键信息
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基因名
MRPS11
- 应用
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别名
28S ribosomal protein S11; 28S ribosomal protein S11 mitochondrial; 28S ribosomal protein S11. mitochondrial precursor; Cervical cancer proto oncogene 2 protein; Cervical cancer proto-oncogene 2 protein; HCC 2; HCC-2; mitochondrial; Mitochondrial ribosomal protein S11; MRP S11; MRP-S11; MRPS11; RPMS11; RT11_HUMAN; S11mt
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P82912
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表达区间
1-194 aa
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氨基酸序列
MQAVRNAGSRFLRSWTWPQTAGRVVARTPAGTICTGARQLQDAAAKQKVEQNAAPSHTKFSIYPPIPGEESSLRWAGKKFEEIPIAHIKASHNNTQIQVVSASNEPLAFASCGTEGFRNAKKGTGIAAQTAGIAAAARAKQKGVIHIRVVVKGLGPGRLSAMHGLIMGGLEVISITDNTPIPHNGCRPRKARKL
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分子量
47 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MRPS11, or Mitochondrial Ribosomal Protein S11, is a crucial component of the mitochondrial ribosome, playing a significant role in mitochondrial protein synthesis. As a part of the 28S mitochondrial ribosomal subunit, MRPS11 is involved in the translation of mitochondrial mRNA, which encodes essential proteins for mitochondrial function. Aberrations in MRPS11 expression and function have been linked to various mitochondrial disorders and diseases, including neurodegenerative conditions and certain forms of cancer. Recent studies have focused on elucidating the precise molecular mechanisms underpinning MRPS11's role in ribosomal assembly and mitochondrial function. Additionally, the exploration of MRPS11 as a potential biomarker for mitochondrial diseases and as a target for therapeutic interventions has gained traction. Understanding the structure-function relationship of MRPS11 and its interactions with other mitochondrial ribosomal proteins is critical for developing strategies to address mitochondrial dysfunctions. Thus, research on MRPS11 not only advances our comprehension of mitochondrial biology but also opens avenues for innovative treatments for mitochondrial-related diseases.
