| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | DPY19L2P1 |
| Uniprot No | Q6NXN4 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-242aa |
| 氨基酸序列 | MKKQGVNPKPLQSSRPSPSKRPYGASPARELEVEKSALGGGKLPGGARRSSPGRIPNLKKRKGLELKVVAKTLLDPFQFVRNSLAQLREEVHELQARWFPSRTTLSIAIFVAILHWLHLVTLFENDRHFSHLSSLEWEMTFRTKMGLYYSYFKTIIEAPSFLEGLWMIMNDRLTEYPLVINTVKRFHLYPEVIIAAWYRTFIGIMNLFGLETKTCWNVTRIEPLNEFKAVKDWEILLAFMLV |
| 分子量 | 54.4 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是为您整理的重组人DPY19L2P1蛋白研究相关的模拟参考文献(均为示例，实际文献请通过PubMed或SciFinder查询)：
1. **《重组人DPY19L2P1蛋白在精子顶体形成中的功能研究》**
- 作者：Smith J, et al.
- 摘要：通过在大肠杆菌系统中表达重组人DPY19L2P1蛋白，研究其与顶体形成关联的机制，证实其通过与膜蛋白互作影响精子形态发生。
2. **《DPY19L2家族假基因DPY19L2P1的重组表达与结构解析》**
- 作者：Chen L, et al.
- 摘要：利用昆虫细胞表达系统获得高纯度重组DPY19L2P1蛋白，并通过X射线晶体学解析其三维结构，揭示其与功能基因DPY19L2的结构差异。
3. **《DPY19L2P1重组蛋白在神经细胞迁移中的作用》**
- 作者：Wang Y, et al.
- 摘要：发现DPY19L2P1在HEK293细胞中重组表达后可通过调控微管稳定性影响神经元迁移，暗示其在神经系统疾病中的潜在功能。
4. **《人DPY19L2P1重组蛋白的免疫原性评估及抗体开发》**
- 作者：Kumar R, et al.
- 摘要：通过哺乳动物细胞表达系统制备重组DPY19L2P1蛋白，并基于该蛋白成功开发出特异性单克隆抗体，为相关疾病的血清学检测提供工具。
**说明**：以上内容为模拟生成的文献案例，实际研究中DPY19L2P1(一种假基因编码蛋白)的相关文献较少。建议通过以下关键词在学术数据库中检索最新进展：
`DPY19L2P1 AND recombinant protein`, `DPY19L2 family AND pseudogene`。
Recombinant human DPY19L2P1 protein is derived from the DPY19L2P1 gene, a pseudogene within the DPY19L (Dpy-19-like) family. This family is implicated in cellular processes such as nuclear envelope organization, ciliogenesis, and spermatogenesis. The functional paralog, DPY19L2. is critical for sperm head elongation and acrosome formation, with its mutations linked to globozoospermia, a male infertility disorder. DPY19L2P1. however, is considered a processed pseudogene lacking protein-coding potential due to frameshifts or premature stop codons. Despite this, pseudogenes can regulate gene expression or encode truncated proteins, sparking interest in characterizing DPY19L2P1’s potential roles. Recombinant DPY19L2P1 is artificially produced via heterologous expression systems (e.g., E. coli or mammalian cells) for structural or functional studies. Researchers aim to explore its interaction partners, enzymatic activities, or regulatory effects, possibly mimicking DPY19L2’s involvement in lipid metabolism or cell polarity. Its study may clarify pseudogene-derived protein contributions to cellular pathways or disease mechanisms. However, evidence for endogenous DPY19L2P1 protein expression remains limited, and its biological relevance is speculative. Current applications include antibody validation, protein interaction screens, or investigating pseudogene translational leakage in health and disease. Further research is needed to validate its physiological significance beyond theoretical frameworks.
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