Recombinant Human FLJ25006 Protein

Recombinant human FLJ25006 protein is a genetically engineered protein derived from the FLJ25006 gene, which encodes a hypothetical protein with limited functional characterization. The FLJ25006 gene, also designated as C22orf32 or chromosome 22 open reading frame 32. is located on human chromosome 22q13.1. While its exact biological role remains unclear, computational analyses suggest it may function as a soluble cytoplasmic or secreted protein potentially involved in cellular signaling or metabolic regulation. Structural predictions indicate conserved domains of unknown function (DUF4697) and weak homology to hydrolase enzymes, though experimental validation is lacking.

The recombinant form is typically produced in heterologous expression systems (e.g., E. coli or mammalian cells) for functional studies. Its production enables investigations into protein-protein interactions, subcellular localization, and biochemical properties. Current research focuses on establishing its physiological relevance through knock-out models and association studies with human diseases, particularly cancers linked to chromosome 22 anomalies. Some preliminary evidence suggests potential involvement in DNA repair pathways or oxidative stress response, but confirmatory studies are needed. As an uncharacterized protein, FLJ25006 represents an emerging target for proteomic exploration, with recombinant versions serving as essential tools for antibody development, structural analysis, and pathway mapping. Challenges persist in elucidating its native expression patterns and regulatory mechanisms across tissues.