Recombinant Human FLJ27505 Protein

Here’s a concise description of recombinant human FLJ27505 protein:

Recombinant human FLJ27505 protein is a genetically engineered version of a poorly characterized protein encoded by the FLJ27505 gene (also known as C1orf123), located on chromosome 1 in humans. This protein belongs to the "uncharacterized protein family" with limited functional annotation in current databases. Structural predictions suggest it may contain conserved domains indicative of enzymatic or regulatory functions, though its exact biological role remains unclear. Recombinant production typically involves heterologous expression systems (e.g., E. coli or mammalian cells) with affinity tags to enable purification and detection.

Interest in this protein stems from emerging links to cellular processes observed in transcriptomic studies, particularly its potential involvement in metabolic regulation or stress responses. Some preliminary studies associate its expression patterns with tumor progression, though validation is ongoing. The recombinant form facilitates biochemical characterization, antibody production, and functional studies to elucidate its molecular interactions and pathways. Current research focuses on resolving its three-dimensional structure, post-translational modifications, and tissue-specific expression profiles to clarify its physiological significance. As an understudied protein, FLJ27505 represents a frontier in proteomic exploration with potential implications for understanding human diseases and developing diagnostic markers.