关键信息
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基因名
Ascl2
- 应用
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别名
Ascl2；BHLHA45；HASH2；Achaete-scute homolog 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99929
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表达区间
1-193aa
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氨基酸序列
MDGGTLPRSA PPAPPVPVGC AARRRPASPE LLRCSRRRRP ATAETGGGAA AVARRNERER NRVKLVNLGF QALRQHVPHG GASKKLSKVE TLRSAVEYIR ALQRLLAEHD AVRNALAGGL RPQAVRPSAP RGPPGTTPVA ASPSRASSSP GRGGSSEPGS PRSAYSSDDS GCEGALSPAE RELLDFSSWL GGY
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分子量
20.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Ascl2, also known as Achaete-Scute Complex Homolog 2, is a transcription factor that plays a crucial role in cellular differentiation and development, especially in the context of neurogenesis and stem cell biology. Its regulation of various target genes is critical for the maintenance of pluripotency and the promotion of lineage specification in embryonic stem cells. Recent studies have highlighted Ascl2's involvement in the development of the central nervous system and its potential role in cancer biology. Research on recombinant Ascl2 protein has gained traction as scientists seek to elucidate its structure-function relationship, understand its molecular mechanisms, and identify its interacting partners. The production of recombinant Ascl2 allows for detailed in vitro studies, enabling researchers to investigate its functionality in cellular contexts and to explore its potential as a therapeutic target. Additionally, understanding Ascl2's role in reprogramming and differentiation could have significant implications for regenerative medicine and the treatment of neurodegenerative diseases. Thus, ongoing research into Ascl2 recombinant protein contributes valuable insights into developmental biology and opens new avenues for targeted therapeutic strategies.
