Cat: PA1000-7923

Recombinant Human Slit1 Protein,His

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关键信息

  • 基因名

    Slit1

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Slit1;KIAA0813;MEGF4;SLIL1;Slit homolog 1 Protein

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O75093

  • 表达区间

    全长

  • 氨基酸序列

    full

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

Slit1, a secreted glycoprotein belonging to the Slit family, plays a crucial role in various biological processes, including neuronal development, axon guidance, and cell migration. Initially identified for its involvement in the regulation of neural pathways, Slit1 has emerged as a key player in the prevention of tumor metastasis and the modulation of immune responses. Its interaction with Robo receptors is instrumental in directing neuronal growth cones and influencing the spatial organization of neurons during neural circuit formation. The study of Slit1, particularly its recombinant protein, has garnered significant attention in biomedical research due to its potential therapeutic implications. Recombinant Slit1 protein allows for the exploration of its structural properties, functional mechanisms, and interaction dynamics with Robo receptors. Furthermore, this research may unlock new avenues for treating neurological disorders and cancers, leveraging Slit1's ability to affect cellular signaling pathways. Understanding the molecular nuances of Slit1's function can facilitate the development of novel therapeutic strategies aimed at enhancing neuronal repair, inhibiting tumor progression, or modulating immune cell behavior. As such, ongoing research into Slit1 recombinant protein not only deepens our understanding of fundamental biological processes but also holds promise for innovative interventions in various diseases.

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