关键信息
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基因名
STK32B
- 应用
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别名
2510009F08Rik; gene for serine/threonine protein kinase; HSA250839; PRO9744; Serine/threonine kinase 32B; Serine/threonine-protein kinase 32B; ST32B_HUMAN; STK32; STK32B; STKG6; UNQ3003; YANK 2; YANK2; Yet another novel kinase 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NY57
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表达区间
1-414 aa
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氨基酸序列
MGGNHSHKPP VFDENEEVNF DHFQILRAIG KGSFGKVCIV QKRDTKKMYA MKYMNKQKCI ERDEVRNVFR ELQIMQGLEH PFLVNLWYSF QDEEDMFMVV DLLLGGDLRY HLQQNVHFTE GTVKLYICEL ALALEYLQRY HIIHRDIKPD NILLDEHGHV HITDFNIATV VKGAERASSM AGTKPYMAPE VFQVYMDRGP GYSYPVDWWS LGITAYELLR GWRPYEIHSV TPIDEILNMF KVERVHYSST WCKGMVALLR KLLTKDPESR VSSLHDIQSV PYLADMNWDA VFKKALMPGF VPNKGRLNCD PTFELEEMIL ESKPLHKKKK RLAKNRSRDG TKDSCPLNGH LQHCLETVRE EFIIFNREKL RRQQGQGSQL LDTDSRGGGQ AQSKLQDGCN NNLLTHTCTR GCSS
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分子量
47.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
The STK32B protein, a member of the serine/threonine kinase family, has garnered significant attention in recent years due to its potential role in various cellular processes and its implications in disease pathology. Research indicates that STK32B is involved in regulating cell proliferation, apoptosis, and signal transduction pathways, which are crucial for maintaining cellular homeostasis. Dysregulation of these processes can lead to diverse health issues, including cancer and metabolic disorders. Scientists are particularly interested in STK32B's interaction with other proteins and its influence on key signaling cascades, such as the mitogen-activated protein kinase (MAPK) pathway. Preliminary studies have shown that overexpression or knockdown of STK32B affects cellular responses to growth factors and stress signals, highlighting its importance in cellular functionality. Furthermore, the exploration of STK32B as a therapeutic target is gaining momentum, as modulating its activity could offer novel strategies for treating diseases linked to its dysregulation. Understanding the structure and function of STK32B through recombinant protein studies is essential for elucidating its biological roles and therapeutic potential. Thus, ongoing research aims to characterize STK32B's functional domains, interactions with other cellular proteins, and its overall impact on cellular health, providing a foundation for future investigations into its applications in drug development and disease treatment.
