关键信息
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基因名
CCK
- 应用
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别名
CCK；CCKRA；Cholecystokinin receptor type A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P07108
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表达区间
2-104aa
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氨基酸序列
WGDLWLLPPASANPGTGTEAEFEKAAEEVRHLKTKPSDEEMLFIYGHYKQATVGDINTERPGMLDFTGKAKWDAWNELKGTSKEDAMKAYINKVEELKKKYGI
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分子量
15.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CCK (Cholecystokinin) is a peptide hormone primarily produced in the small intestine that plays a crucial role in digestion and appetite regulation. It stimulates the gallbladder to contract and release bile, facilitating fat digestion, and triggers the release of digestive enzymes from the pancreas. The CCK receptor is also involved in signaling pathways that regulate satiety, making it a target for obesity and metabolic disorder research. Recent studies have focused on the recombinant production of CCK proteins to better understand their structure-function relationships and therapeutic potential. The use of recombinant DNA technology allows researchers to produce large quantities of CCK for various applications, including drug development and the study of gastrointestinal diseases. Moreover, understanding how CCK interacts with its receptors could lead to novel treatments for conditions such as obesity, eating disorders, and chronic pancreatitis. Overall, the exploration of recombinant CCK proteins represents a significant advancement in both fundamental and clinical research concerning gastrointestinal physiology and metabolism.
