关键信息
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基因名
LPHN2
- 应用
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别名
LPHN2；KIAA0786；LEC1；LPHH1；Adhesion G Protein-coupled receptor L2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95490
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
LPHN2, also known as latrophilin-2, is a member of the adhesion G protein-coupled receptor (aGPCR) family, which plays a critical role in cell-cell interactions, synapse formation, and neuronal signaling. Its expression has been implicated in various biological processes, including neural development and immune responses. Recent studies have linked LPHN2 to psychiatric disorders such as schizophrenia and attention deficit hyperactivity disorder (ADHD), highlighting its potential importance in understanding neurodevelopmental and neurological conditions. The investigation of LPHN2 recombinant protein focuses on its structural and functional properties, providing insights into its signaling pathways and interactions with ligands and other cellular components. Researchers aim to explore the therapeutic potential of targeting LPHN2 to modulate related pathways and address associated disorders. By characterizing LPHN2 in detail, including its receptor mechanisms and downstream effects, scientists hope to unravel the complexities of its role in the central nervous system and identify new avenues for therapeutic intervention. This research not only contributes to the foundational understanding of aGPCR biology but also opens up possibilities for novel treatments for mental health conditions influenced by LPHN2 dysregulation.
