关键信息
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基因名
LCN12
- 应用
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别名
LCN12；Epididymal-specific lipocalin-12
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6JVE5
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表达区间
20-192aa
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氨基酸序列
Q TPTPLPLPPP MQSFQGNQFQ GEWFVLGLAG NSFRPEHRAL LNAFTATFEL SDDGRFEVWN AMTRGQHCDT WSYVLIPAAQ PGQFTVDHGV EPGADREETR VVDSDYTQFA LMLSRRHTSR LAVLRISLLG RSWLLPPGTL DQFICLGRAQ GLSDDNIVFP DVTGWSPQAS VC
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
LCN12 (lipocalin 12) is a member of the lipocalin protein family known for its ability to bind small hydrophobic molecules. It is primarily expressed in human tissues, particularly in the skin and lungs, implicating its potential role in various physiological processes such as immune response, cellular trafficking, and tissue homeostasis. Research on LCN12 has gained momentum due to its association with inflammatory conditions and its emerging role in cancer progression, where it may influence tumor microenvironments and interactions with immune cells. The interest in recombinant LCN12 protein has been fueled by its potential applications in therapeutic interventions and diagnostics. Understanding its structure and function at a molecular level can provide insights into its mechanism of action and pave the way for novel treatments targeting LCN12-related pathways. Consequently, studies often focus on the successful expression and purification of recombinant LCN12, ensuring that the protein maintains its biological activity. This foundational research contributes to unraveling the complex biological functions of LCN12, offering opportunities to explore its potential as a biomarker or a therapeutic target in various diseases.
