| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | Gbal |
| Uniprot No | A0A1L8FDF0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-519aa |
| 氨基酸序列 | MWSWFLPILGVLVLARGSSGGRLCAPLNFGQSSVVCQCNATYCDTLDPIVVPSVGNFSVYETSQSGKRLQVMSGTFTKRQPSPMDLVLTLNDKKKFQTIKGFGGAVTDSAALNILSLSDETKENLLRSYFSEEGIGYNILRVPMGSCDFSTRIYTYLDTEGDFSMKTFSLQVEDTKLKIPLIQKAKELSNRSISLFASPWTSPPWMKTNGAITGKGTLKGKPGDQYHKTWANYFIRFLDEYAKLNVTFWAVTVENEPTAGLVTDYPFQSLGFTPEHMRDFIASDLGPAFANSSHKQVKIMILDDNRLLLPYWAKVILSDLKAARYVHGIAVHWYLDAIVPADVTLGRTHQLYPDYFLFASEACTGFTPWNKGVQLGCWDRGNQYSHRIIEDLNYYVTGWTDWNLALDIEGGPTWVENNVDSPIIVDLSKDVFYKQPMFYHMAHFSKFIPEGSRRVGLDLNQGSQLETVAFLSPDGSVAVVVVLNRESVDVKFLISDPSLGVIDTVSPANSIQTYIWRRQ |
| 预测分子量 | 58,1 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是基于您提供的查询生成的模拟参考文献示例(请注意，“Gbal重组蛋白”可能为虚构或特定领域术语，建议核实名称或补充背景信息)：
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1. **名称**: *Expression and Functional Analysis of Gbal Recombinant Protein in Mammalian Cells*
**作者**: Li, X. et al.
**摘要**: 本研究报道了Gbal重组蛋白在HEK293细胞中的高效表达与纯化，并验证了其在细胞信号转导中的潜在作用。实验表明Gbal可能通过与特定膜受体结合调控下游激酶活性，为相关疾病治疗提供新靶点。
2. **名称**: *Structural Characterization of Gbal Recombinant Protein Using Cryo-EM*
**作者**: Smith, J.R. & Wang, Y.
**摘要**: 通过冷冻电镜技术解析了Gbal重组蛋白的三维结构，揭示了其独特的α-螺旋结构域和可能的配体结合位点。该结构数据为设计靶向Gbal的小分子药物奠定了基础。
3. **名称**: *Gbal Recombinant Protein Enhances Immune Response in Vaccine Development*
**作者**: Kumar, S. et al.
**摘要**: 研究发现，将Gbal重组蛋白作为疫苗佐剂可显著增强小鼠模型中对流感病毒的特异性抗体反应，提示其在疫苗开发中的潜在应用价值。
4. **名称**: *Optimization of Gbal Recombinant Protein Production in E. coli*
**作者**: Chen, L. & Zhang, H.
**摘要**: 通过优化大肠杆菌表达系统的培养条件和诱导策略，将Gbal重组蛋白的产量提高了3倍，并验证了其体外生物活性，为工业化生产提供了可行方案。
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**建议**：若“Gbal”为特定领域术语或存在拼写误差(如可能指“GABA受体相关蛋白”或“Galectin重组蛋白”)，建议使用PubMed、Web of Science等数据库，结合准确关键词(如“Gbal recombinant protein function”)检索真实文献。
Gbal recombinant protein is a genetically engineered biomolecule designed for diverse applications in biotechnology and biomedical research. Derived from the fusion or modification of native protein sequences, Gbal is typically produced using recombinant DNA technology, where specific gene fragments are inserted into host organisms (e.g., *E. coli*, yeast, or mammalian cells) to enable large-scale expression. The name "Gbal" may reflect its functional domains or target specificity, though its exact nomenclature origin varies across contexts. Such proteins are often optimized for enhanced stability, solubility, or binding affinity compared to their wild-type counterparts.
In structural terms, Gbal may incorporate functional motifs like receptor-binding domains, enzymatic active sites, or signaling peptides, tailored to interact with specific cellular targets. Its design often aligns with therapeutic or diagnostic goals, such as neutralizing pathogens, modulating immune responses, or serving as a detection tool in assays. For instance, Gbal variants might mimic viral surface proteins for vaccine development or block inflammatory cytokines in autoimmune diseases.
Research on Gbal-like recombinant proteins has surged due to their versatility in addressing unmet medical needs, including cancer immunotherapy, infectious disease treatment, and regenerative medicine. They also play roles in industrial enzymes and biosensors. Challenges remain in optimizing expression yields, minimizing immunogenicity, and ensuring proper post-translational modifications. Advances in protein engineering, such as directed evolution or AI-driven design, continue to refine Gbal's functionality, underscoring its potential as a cornerstone in next-generation biologics.
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