| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/30-1/150 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/10000 | Human,Mouse,Rat |
| Aliases | TSC21; C2orf51 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human TEX37 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于TEX37抗体的虚构参考文献示例(请注意，这些文献为模拟内容，实际研究中可能需要进一步验证)：
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1. **文献名称**: "Development of a Polyclonal Antibody Against TEX37 for Germ Cell-Specific Protein Analysis"
**作者**: Johnson R, et al.
**摘要**: 本研究报道了一种针对人类TEX37蛋白的多克隆抗体的开发与验证。通过免疫印迹和免疫组织化学实验证实了抗体在睾丸组织中的特异性，揭示了TEX37在精子发生早期阶段的表达模式，提示其可能在生殖细胞成熟中发挥作用。
2. **文献名称**: "TEX37 as a Novel Biomarker in Ovarian Cancer: Validation by a Custom Monoclonal Antibody"
**作者**: Lee S, et al.
**摘要**: 研究团队开发了一种小鼠单克隆抗体，用于检测TEX37在卵巢癌组织中的表达。实验表明，TEX37在高级别浆液性癌中显著高表达，并与肿瘤侵袭性相关，为预后评估提供了潜在工具。
3. **文献名称**: "Immunolocalization of TEX37 in Mouse Testis Using a Species-Specific Antibody"
**作者**: Martinez P, et al.
**摘要**: 利用新开发的小鼠TEX37特异性抗体，通过免疫荧光技术明确了该蛋白在睾丸生精小管中的定位，发现其在减数分裂后精细胞中富集，支持了TEX37参与染色质重塑的假设。
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**建议**：若需真实文献，请通过PubMed、Google Scholar等平台以关键词“TEX37 antibody”或“TEX37 immunohistochemistry”检索，并关注生殖生物学、癌症标志物等领域的研究。部分研究可能未在标题中直接提及抗体，但方法学部分可能包含相关信息。
The TEX37 antibody targets the protein encoded by the TEX37 gene, a member of the cancer/testis (CT) antigen family. CT antigens are characterized by their restricted expression in germline cells (primarily testes) and aberrant reactivation in various cancers. TEX37. initially identified through genomic and transcriptomic analyses, exhibits testis-specific expression under normal physiological conditions. However, its ectopic expression has been detected in malignancies such as melanoma, lung, and breast cancers, suggesting potential roles in oncogenesis or cancer progression.
TEX37 antibodies are primarily used as research tools to investigate the protein's expression patterns, subcellular localization, and functional mechanisms. Their applications include immunohistochemistry (IHC), Western blotting (WB), and immunofluorescence (IF) to validate TEX37 overexpression in tumor tissues compared to normal counterparts. Such studies aim to explore its utility as a diagnostic biomarker or immunotherapeutic target, leveraging the immune system's ability to recognize CT antigens.
Current research focuses on understanding TEX37's biological significance, including its involvement in cell proliferation, apoptosis, or immune evasion. Challenges remain in elucidating its precise molecular pathways and clinical relevance across cancer types. Despite limited data, TEX37 antibodies hold promise for advancing cancer biology and therapeutic strategies, particularly in personalized oncology. Further validation is required to establish their diagnostic or therapeutic viability.
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