| WB | 1/200-1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| WB Predicted band size | 35 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Full length fusion protein |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于GAS2抗体的3篇参考文献示例(注：内容为模拟概括，实际文献需根据具体数据库检索验证)：
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1. **文献名称**：*"GAS2 regulates apoptosis and cytoskeletal organization during embryonic development"*
**作者**：Smith J, et al.
**摘要**：该研究通过免疫印迹和免疫荧光技术，利用GAS2特异性抗体揭示了GAS2蛋白在胚胎发育过程中调控细胞凋亡和微管骨架重排的作用，证明其缺失导致发育异常。
2. **文献名称**：*"Growth Arrest-Specific Protein 2 (GAS2) in cancer: A novel biomarker for tumor progression"*
**作者**：Li X, Wang Y.
**摘要**：文章通过免疫组化分析(使用GAS2抗体)发现GAS2在多种癌症中高表达，并与肿瘤侵袭性相关，提示其可作为潜在治疗靶点或预后标志物。
3. **文献名称**：*"Mechanical stress-induced GAS2 activation modulates cell adhesion through actin remodeling"*
**作者**：Garcia R, et al.
**摘要**：研究利用GAS2抗体进行蛋白质定位分析，发现机械应力通过激活GAS2介导的肌动蛋白重组，影响细胞黏附和迁移能力，为力学信号转导机制提供新见解。
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如需具体文献，建议通过PubMed或Google Scholar检索关键词“GAS2 antibody”或“GAS2 immunolocalization”获取最新研究。
**Background of GAS2 Antibody**
The Growth Arrest-Specific 2 (GAS2) protein, encoded by the *GAS2* gene, is a member of the GAS family implicated in cellular processes linked to growth arrest, cytoskeletal organization, and apoptosis. Initially identified for its upregulation during cell cycle arrest, GAS2 interacts with microtubules and microfilaments, playing a role in maintaining cytoskeletal architecture and mediating structural changes during apoptosis. Structurally, it contains a calponin homology (CH) domain for actin binding and a Gas2-like domain for microtubule association, enabling cross-linking of cytoskeletal components.
GAS2 antibodies are essential tools for studying its expression, localization, and function in cellular models. They are widely used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to explore GAS2's regulatory roles in cell cycle arrest, apoptosis, and tissue development. Dysregulation of GAS2 has been associated with pathologies, including cancer and developmental disorders, making its antibody valuable in biomedical research. For instance, in cancer studies, GAS2 antibodies help assess its tumor-suppressive or oncogenic roles, depending on cellular context. Additionally, these antibodies aid in characterizing post-translational modifications (e.g., phosphorylation) that modulate GAS2 activity. Researchers prioritize antibodies validated for specificity, often targeting unique epitopes to avoid cross-reactivity with homologous proteins like GAS2L1 or GAS2L3. Overall, GAS2 antibodies are pivotal in unraveling cytoskeletal dynamics and their implications in health and disease.
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