| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | ALS2CR11 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human C2CD6 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于C2CD6抗体的模拟参考文献示例(注：文献信息为假设性示例，实际引用需核实)：
1. **文献名称**: "C2CD6 as a novel biomarker in papillary thyroid carcinoma: Expression and functional analysis"
**作者**: Li X, et al.
**摘要**: 研究利用C2CD6抗体通过免疫组化(IHC)和Western blot技术，发现C2CD6在甲状腺乳头状癌中高表达，并证实其通过调控Wnt/β-catenin通路促进肿瘤侵袭。
2. **文献名称**: "Proteomic characterization of C2CD6 in lung adenocarcinoma progression"
**作者**: Wang Y, et al.
**摘要**: 通过C2CD6特异性抗体进行质谱分析和免疫荧光染色，揭示C2CD6在肺腺癌转移中的关键作用，与患者预后不良显著相关。
3. **文献名称**: "C2CD6 interacts with HER2 signaling to drive breast cancer cell proliferation"
**作者**: Chen R, et al.
**摘要**: 研究采用C2CD6抗体进行共免疫沉淀(Co-IP)实验，证明C2CD6与HER2蛋白互作，增强乳腺癌细胞的增殖能力，提示其作为治疗靶点的潜力。
4. **文献名称**: "The role of C2CD6 in pancreatic cancer stem cell maintenance"
**作者**: Zhang H, et al.
**摘要**: 通过流式细胞术和免疫印迹(使用C2CD6抗体)发现，C2CD6通过维持肿瘤干细胞特性促进胰腺癌耐药性，敲低后显著抑制肿瘤球形成。
**注意**：以上文献为模拟内容，实际研究中请通过PubMed或学术数据库检索真实文献。若需具体文献支持，建议补充C2CD6的研究方向(如疾病类型或分子机制)。
The C2CD6 (C2 Calcium-Dependent Domain Containing 6) antibody is a research tool designed to detect and study the C2CD6 protein, a member of the C2 domain-containing protein family. The C2CD6 gene encodes a protein implicated in calcium-dependent signaling pathways, though its precise biological functions remain under investigation. C2CD6 contains a conserved C2 domain, a structural motif known to bind phospholipids in a calcium-dependent manner, suggesting potential roles in membrane trafficking, signal transduction, or synaptic regulation.
Antibodies targeting C2CD6 are primarily used in basic research to explore its expression, localization, and interactions in cellular or tissue contexts. For example, studies employ techniques like Western blotting, immunohistochemistry, or immunofluorescence to map C2CD6 distribution in organs such as the brain, testes, or thyroid, where it may regulate specialized processes. Some evidence links C2CD6 to cancer progression, with altered expression observed in malignancies like hepatocellular carcinoma, prompting interest in its diagnostic or therapeutic potential.
Available as polyclonal or monoclonal variants, C2CD6 antibodies are typically validated for specificity and sensitivity in model systems. Researchers also utilize them to investigate C2CD6’s interaction partners, such as calcium channels or vesicular proteins, to unravel its role in cellular homeostasis. Despite growing interest, further functional studies are needed to clarify its mechanisms and relevance to disease pathways.
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