Rabbit Polyclonal ELF1 Antibody

The ELF1 antibody is a crucial tool in molecular and cellular biology research, targeting the Ets family transcription factor ELF1 (E74-like factor 1). ELF1 regulates gene expression by binding to specific DNA sequences via its conserved Ets domain, influencing processes such as immune response, cell differentiation, and apoptosis. It plays a significant role in T-cell development, cytokine production, and oncogenesis, with dysregulation linked to cancers like leukemia and lymphoma. Researchers use ELF1 antibodies to detect and quantify ELF1 protein levels in techniques such as Western blotting, immunohistochemistry, and chromatin immunoprecipitation (ChIP). These applications help elucidate ELF1’s functional mechanisms, its interaction with signaling pathways (e.g., MAPK/ERK), and its involvement in disease progression. Available as monoclonal or polyclonal variants, ELF1 antibodies are typically validated for specificity to minimize cross-reactivity with related Ets proteins. Recent studies also explore ELF1’s epigenetic roles, including histone modification and chromatin remodeling. As a biomarker, ELF1 expression patterns are investigated for diagnostic or therapeutic potential in oncology and immunology, underscoring the antibody’s importance in both basic research and clinical applications.