Rabbit Polyclonal WDR41 Antibody

WDR41 (WD repeat domain 41) is a protein encoded by the WDR41 gene, belonging to the WD-repeat protein family characterized by conserved motifs facilitating protein-protein interactions. It plays roles in diverse cellular processes, including autophagy, vesicle trafficking, and signaling pathways. Studies suggest its involvement in regulating lysosomal function and mTORC1 signaling, linking it to neurodegenerative diseases and cancer. WDR41 antibodies are essential tools for investigating its expression, localization, and molecular interactions. These antibodies are typically developed in hosts like rabbits or mice using immunogenic peptides or recombinant protein fragments. They are validated for specificity through techniques like Western blotting, immunofluorescence, and immunoprecipitation, often using knockout controls. Commercially available WDR41 antibodies enable research into its role in pathologies such as Parkinson’s disease, where WDR41 dysfunction may impair autophagy-lysosomal pathways. Recent studies also explore its potential as a biomarker or therapeutic target in tumors. However, antibody performance can vary, requiring careful optimization of experimental conditions. Ongoing research aims to clarify WDR41’s precise mechanisms, driving demand for reliable antibodies to support basic and translational studies.