Rabbit Polyclonal MYBPHL Antibody

The MYBPHL (Myosin Binding Protein H-like) antibody is a tool used to study the MYBPHL protein, a member of the myosin-binding protein family. MYBPHL shares structural similarities with myosin-binding protein C (MYBPC), which is critical for sarcomere organization and muscle contraction. While MYBPHL's exact biological role remains less defined, studies suggest its involvement in modulating myosin function, potentially influencing cytoskeletal dynamics and cellular motility. It is expressed in various tissues, including skeletal muscle, heart, and certain epithelial cells. Research on MYBPHL has gained traction due to its possible links to diseases. For instance, altered MYBPHL expression has been observed in cancers, where it may contribute to tumor progression or metastasis. Additionally, its interaction with myosin motors hints at roles in neurodevelopmental or neuromuscular disorders. The MYBPHL antibody is primarily utilized in techniques like Western blotting, immunohistochemistry, and immunofluorescence to detect protein expression, localization, and post-translational modifications. Its development often involves immunizing hosts with peptide sequences unique to MYBPHL to ensure specificity. Current studies focus on unraveling its mechanistic pathways and validating its potential as a biomarker or therapeutic target. Further exploration of MYBPHL could enhance understanding of cellular mechanics and disease pathology.