| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Full length fusion protein |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于ZNF672抗体的3篇文献示例(注：以下内容为模拟示例，具体文献需根据实际数据库检索确认)：
1. **文献名称**：*ZNF672 regulates epigenetic silencing in hepatocellular carcinoma through antibody-validated chromatin interaction*
**作者**：Li X, et al.
**摘要**：该研究利用自研的ZNF672抗体，通过ChIP-seq技术验证了ZNF672蛋白在肝癌细胞中与特定DNA区域的结合，揭示其通过表观调控抑制肿瘤抑制基因的机制。
2. **文献名称**：*Development and application of a polyclonal antibody against ZNF672 for analyzing its expression in neural tissues*
**作者**：Wang Y, et al.
**摘要**：作者报道了一种新型兔源多克隆ZNF672抗体的开发，并通过免疫组化和Western blot证实其在人脑组织中的特异性表达，提示ZNF672可能参与神经发育调控。
3. **文献名称**：*ZNF672 antibody-based screening identifies its role in DNA damage repair*
**作者**：Chen H, et al.
**摘要**：研究使用商业化ZNF672抗体进行免疫共沉淀(Co-IP)，发现ZNF672与DNA修复蛋白复合物相互作用，提示其在维持基因组稳定性中的潜在功能。
如需具体文献，建议通过PubMed或Google Scholar以“ZNF672 antibody”为关键词检索近年研究。
The ZNF672 antibody is a specialized tool used to detect and study the Zinc Finger Protein 672 (ZNF672), a member of the zinc finger protein family. Zinc finger proteins are characterized by finger-like structural domains that bind to DNA or RNA, playing critical roles in transcriptional regulation, chromatin remodeling, and cellular differentiation. ZNF672. encoded by the *ZNF672* gene on human chromosome 1q25.3. is hypothesized to function as a transcriptional regulator, though its precise biological mechanisms remain under investigation. Studies suggest its involvement in gene silencing, cell cycle control, and potential roles in neurodevelopment or cancer progression, as aberrant expression has been observed in certain tumors and neurological disorders.
ZNF672 antibodies are typically polyclonal or monoclonal antibodies generated by immunizing hosts (e.g., rabbits or mice) with synthetic peptides or recombinant protein fragments corresponding to specific epitopes of ZNF672. These antibodies enable researchers to identify ZNF672 in techniques like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and chromatin immunoprecipitation (ChIP). Validation parameters, including specificity (via knockout controls), cross-reactivity, and optimal dilution ratios, are critical to ensure reliable results.
Research utilizing ZNF672 antibodies has contributed to understanding its expression patterns across tissues, subcellular localization (primarily nuclear), and interactions with other regulatory proteins. Such studies aim to unravel its role in disease pathways or developmental processes, highlighting its potential as a biomarker or therapeutic target. Commercial availability of ZNF672 antibodies from multiple suppliers has facilitated its integration into diverse experimental workflows in molecular biology and clinical research.
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