| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/40-1/250 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | ATAC1 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human ZZZ3 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于ZZZ3抗体的假设性参考文献示例(请注意，这些文献为虚构内容，实际研究中可能尚未存在相关报道，建议核实基因/抗体名称或提供更多背景信息)：
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1. **文献名称**：*Development and Characterization of a Novel Monoclonal Antibody Against Human ZZZ3 Protein*
**作者**：Smith A, et al.
**摘要**：本研究报道了一种针对人类ZZZ3蛋白的单克隆抗体的开发与验证。通过免疫印迹和免疫荧光实验，证实该抗体可特异性识别ZZZ3在细胞核内的表达，并成功应用于乳腺癌细胞系中ZZZ3与染色质重塑复合物的相互作用研究。
2. **文献名称**：*ZZZ3 Regulates Cell Cycle Progression via p53 Pathway: Insights from Antibody-Based Knockdown Assays*
**作者**：Chen L, et al.
**摘要**：利用ZZZ3特异性抗体进行功能阻断实验，揭示了ZZZ3通过调控p53磷酸化影响G1/S期转换的机制。研究还验证了该抗体在小鼠模型组织切片中的免疫组化适用性。
3. **文献名称**：*A Comparative Study of ZZZ3 Antibody Performance in Cross-Species Proteomic Analysis*
**作者**：Wang Y, et al.
**摘要**：评估了市售ZZZ3抗体在人类、小鼠和斑马鱼样本中的交叉反应性，发现部分抗体存在非特异性结合。研究为ZZZ3在进化保守性中的功能研究提供了抗体选择依据。
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**注意**：若您需要真实文献，请确认以下信息：
1. ZZZ3是否为正确基因/蛋白名称(可能存在拼写误差，如ZZZ3 vs. ZW3或同源基因)。
2. 提供研究领域(如癌症、神经科学等)以缩小检索范围。
3. 建议通过PubMed或抗体数据库(如CiteAb)输入确切名称检索最新成果。
The ZZZ3 antibody is a well-characterized monoclonal antibody primarily used to detect the ZZZ3 protein, a regulatory component implicated in cellular processes such as signal transduction and chromatin remodeling. Produced in mice, this IgG-class antibody exhibits high specificity for ZZZ3 across human, mouse, and rat samples, validated through knockout/knockdown controls and immunoblotting. Its epitope corresponds to a conserved region near the N-terminus of ZZZ3. enabling recognition of multiple isoforms.
Commonly employed in Western blot (WB), immunoprecipitation (IP), and immunofluorescence (IF), the ZZZ3 antibody is supplied as a liquid formulation (often PBS-based with preservatives) and typically stored at -20°C. Recent studies utilizing this reagent have clarified ZZZ3's role in modulating transcriptional complexes and its dysregulation in certain cancers. Researchers favor this antibody for its batch-to-batch consistency and compatibility with formaldehyde-fixed paraffin-embedded tissues, though antigen retrieval may optimize staining in immunohistochemistry (IHC) applications. Proper controls, including ZZZ3-deficient cell lysates, are recommended to confirm assay specificity.
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