| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | CN2; CPGL; PEPA; HsT2298; HEL-S-13 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human CNDP2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于CNDP2抗体的模拟参考文献示例(注：以下内容为虚构，仅用于示例格式参考)：
1. **"CNDP2 Expression in Human Hepatocellular Carcinoma and Its Clinical Significance"**
- **作者**: Zhang L, Wang Y, Chen J.
- **摘要**: 本研究通过免疫组化技术结合CNDP2抗体，分析了CNDP2蛋白在肝癌组织中的表达水平，发现其高表达与患者预后不良相关，提示CNDP2可能作为肝癌治疗的潜在靶点。
2. **"Development of a Monoclonal Antibody Specific to CNDP2 for Neurological Disease Research"**
- **作者**: Smith KA, et al.
- **摘要**: 报道了一种新型CNDP2单克隆抗体的开发与验证，该抗体通过Western blot和免疫荧光证实特异性，并应用于阿尔茨海默病模型小鼠脑组织中CNDP2蛋白的定位研究。
3. **"CNDP2 Antibody-Based Detection of Carnosine Metabolism Dysregulation in Diabetes"**
- **作者**: Gupta R, Lee S.
- **摘要**: 利用CNDP2抗体探究了糖尿病患者肌肉组织中肌肽代谢酶CNDP2的表达变化，发现其表达下调可能与糖尿病并发症中的氧化应激增强有关。
4. **"CNDP2 as a Biomarker for Renal Fibrosis: Validation by Antibody Staining"**
- **作者**: Tanaka M, et al.
- **摘要**: 通过CNDP2抗体对肾纤维化动物模型的组织样本进行分析，证实CNDP2在肾小管间质中的异常积累与纤维化进程相关，提示其作为临床生物标志物的潜力。
**备注**：以上文献及内容均为模拟示例，实际研究中请通过PubMed、Web of Science等数据库检索真实发表的论文。
**Background of CNDP2 Antibody**
The CNDP2 (Carnosine Dipeptidase 2) gene encodes a cytosolic enzyme belonging to the M20 metalloprotease family, primarily involved in hydrolyzing dipeptides such as carnosine and homocarnosine. These dipeptides play roles in cellular antioxidant defense, pH buffering, and neurological modulation. CNDP2 is expressed in various tissues, including the liver, kidney, and brain, and its activity is linked to metabolic and neurodegenerative pathways.
CNDP2 antibodies are immunological tools designed to detect and study the expression, localization, and function of the CNDP2 protein. Research has highlighted its potential relevance in diseases like diabetes, cancer, and Alzheimer’s, where altered carnosine metabolism or oxidative stress may contribute to pathology. For instance, CNDP2 polymorphisms are associated with diabetic nephropathy risk, while its dysregulation in tumors suggests a role in cancer cell survival.
These antibodies are widely used in techniques like Western blotting, immunohistochemistry, and ELISA to explore CNDP2’s biological mechanisms or validate its involvement in disease models. Their development and specificity are critical for advancing studies on metabolic regulation, neurodegeneration, and therapeutic targeting.
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