WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/25-1/100 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
WB Predicted band size | 59 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human DALRD3 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
+ +
以下是关于DALRD3抗体的示例参考文献(部分内容可能为虚构,实际文献需通过学术数据库查询):
1. **文献名称**:*DALRD3 as a Novel RNA-Binding Protein Involved in Ribosome-Associated Quality Control*
**作者**:Smith A, et al.
**摘要**:本研究揭示了DALRD3蛋白在核糖体相关质量控制中的作用,通过特异性抗体验证其与假尿嘧啶修饰RNA的结合能力,并证明其在调控翻译停滞中的作用。
2. **文献名称**:*DALRD3 Antibody Development for Glioblastoma Biomarker Discovery*
**作者**:Chen L, et al.
**摘要**:开发了一种高特异性DALRD3单克隆抗体,用于胶质母细胞瘤组织样本分析,发现DALRD3表达与肿瘤侵袭性和患者预后显著相关。
3. **文献名称**:*Structural and Functional Characterization of DALRD3 in tRNA Modification*
**作者**:Wang Y, et al.
**摘要**:利用免疫共沉淀(Co-IP)和Western blot技术,结合DALRD3抗体,阐明其与假尿嘧啶合成酶复合物的相互作用,揭示其在tRNA修饰中的分子机制。
4. **文献名称**:*DALRD3 Knockout Mouse Model Reveals Immune Regulation Defects*
**作者**:Garcia R, et al.
**摘要**:通过DALRD3抗体验证基因敲除小鼠模型,发现DALRD3缺失导致T细胞功能异常,提示其在免疫调节中的潜在作用。
**注意**:以上文献为示例性质,实际研究需通过PubMed、Web of Science等平台检索。如需真实文献,建议使用关键词"DALRD3 antibody"或"DALRD3 function"进行查询。
The DALRD3 (DALR anticodon binding domain containing 3) protein is encoded by the DALRD3 gene and is characterized by the presence of a conserved DALR domain, which is implicated in tRNA recognition and translation regulation. This domain, shared with other tRNA-modifying enzymes, suggests DALRD3's potential role in RNA binding or post-transcriptional modification processes. While its precise biological function remains under investigation, DALRD3 is hypothesized to influence cellular pathways related to protein synthesis, cell cycle progression, or stress responses. Studies have linked it to interactions with components of the translational machinery, though its mechanistic contributions are not fully elucidated.
DALRD3 antibodies are immunological tools developed to detect and study the expression, localization, and molecular interactions of the DALRD3 protein. These antibodies are commonly used in techniques such as Western blotting, immunofluorescence, and immunoprecipitation to explore DALRD3's tissue distribution, subcellular localization (e.g., cytoplasmic or nuclear), and expression changes under physiological or pathological conditions. Some research suggests DALRD3 may be dysregulated in cancers or neurological disorders, making its antibodies valuable for biomarker discovery or functional studies. Commercial DALRD3 antibodies are typically raised in hosts like rabbits or mice, with validation data confirming specificity against conserved epitopes. Ongoing research aims to clarify DALRD3's role in disease and its potential as a therapeutic target.
×