Rabbit Polyclonal SLC22A24 Antibody

The SLC22A24 antibody is a research tool designed to detect and analyze the SLC22A24 protein, a member of the solute carrier family 22 (SLC22). This family comprises transmembrane transporters involved in the uptake or excretion of endogenous organic ions, drugs, and toxins. SLC22A24. though less characterized than other SLC22 members like OATs (organic anion transporters) or OCTs (organic cation transporters), is hypothesized to play a role in small molecule transport, potentially influencing drug metabolism or detoxification pathways. It is expressed in tissues such as the liver, kidney, and intestine, suggesting involvement in systemic homeostasis. The antibody enables studies on SLC22A24's expression patterns, subcellular localization, and regulatory mechanisms, aiding investigations into its physiological or pathological roles. Current research focuses on its potential association with metabolic disorders, renal or hepatic diseases, and chemotherapeutic response variability. Commercial SLC22A24 antibodies are typically developed in hosts like rabbits or mice, validated for applications such as Western blotting, immunohistochemistry, or immunofluorescence. However, specificity and cross-reactivity challenges may arise due to sequence homology within the SLC22 family. Ongoing studies aim to clarify SLC22A24's substrate specificity, transport kinetics, and genetic polymorphisms, with the antibody serving as a critical reagent in these explorations.