| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/300 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | COX, COX8, VIII, COX8L, COX8-2, VIII-L |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human COX8A |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
+ +
以下是关于MPP1抗体的3篇虚构参考文献示例(基于领域常见研究方向)：
1. **文献名称**：*"MPP1 Antibody Characterization and Its Role in Erythrocyte Membrane Stability"*
**作者**：Sung, L., et al.
**摘要**：本研究开发了一种高特异性兔源多克隆MPP1抗体，验证了其在免疫印迹和免疫荧光中对人红细胞膜中MPP1蛋白的识别能力，揭示了MPP1与血影蛋白复合物的相互作用，并证明其在维持细胞形态中的关键作用。
2. **文献名称**：*"MPP1 Deficiency in Hereditary Spherocytosis Detected by Novel Monoclonal Antibody"*
**作者**：Baines, A.J., et al.
**摘要**：通过新开发的小鼠单克隆抗体(克隆号：α-MPP1-3C7)，研究者发现遗传性球形红细胞增多症患者中MPP1表达显著降低，并证实其缺失导致膜稳定性受损，为疾病诊断提供了新工具。
3. **文献名称**：*"Localization of MPP1 in Lipid Rafts Using Immunogold Electron Microscopy"*
**作者**：Salomao, M., et al.
**摘要**：利用抗MPP1抗体结合免疫金标记技术，本研究首次在质膜脂筏中定位了MPP1.揭示了其在膜微结构域信号传导中的潜在功能，并验证了抗体在超微结构分析中的适用性。
(注：以上文献为模拟示例，实际引用请查询PubMed或SciHub等学术平台。)
The MPP1 (Membrane Palmitoylated Protein 1) antibody is a tool used to study the MPP1 protein, a member of the membrane-associated guanylate kinase (MAGUK) family. MPP1. also known as PALS2 or DXS552. plays a critical role in organizing cell membrane structures, particularly in erythrocytes. It stabilizes the plasma membrane by interacting with cytoskeletal components and other proteins, such as protein 4.1 and glycophorin C, contributing to red blood cell elasticity and integrity. Mutations in the MPP1 gene are linked to X-linked hereditary spherocytosis, a rare hematological disorder characterized by fragile, spherical erythrocytes.
The MPP1 antibody is widely employed in research to investigate cell polarity, membrane protein complexes, and erythrocyte disorders. It aids in detecting MPP1 expression via techniques like Western blotting, immunofluorescence, and flow cytometry. Studies also utilize this antibody to explore MPP1's role in non-erythroid cells, including its involvement in neuronal development and epithelial cell junctions. Its specificity for MPP1 makes it valuable for elucidating disease mechanisms and validating protein interactions in membrane scaffolding processes. Overall, the MPP1 antibody serves as a key reagent in both basic research and diagnostic investigations related to membrane biology and hematological pathologies.
×
