| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/70-1/350 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| WB Predicted band size | 71 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human GSTCD |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
+ +
以下是关于GSTCD抗体的3篇参考文献及其摘要概括(注：文献为虚拟示例，实际研究中需根据真实数据库检索)：
1. **文献名称**：*"GSTCD regulates extracellular matrix remodeling in pulmonary fibrosis via TGF-β signaling"*
**作者**：Smith J, et al.
**摘要**：本研究通过免疫印迹和免疫荧光技术，利用GSTCD特异性抗体揭示了GSTCD蛋白在肺成纤维细胞中的表达定位，并证实其通过调控TGF-β通路参与细胞外基质重塑，可能影响慢性肺病的进展。
2. **文献名称**：*"Genetic and functional analyses of GSTCD in asthma susceptibility"*
**作者**：Lee S, et al.
**摘要**：该研究结合GWAS数据和体外实验，使用GSTCD抗体检测哮喘患者气道组织的蛋白表达水平，发现GSTCD基因变异可能导致蛋白表达下调，与气道高反应性及炎症相关。
3. **文献名称**：*"Characterization of a novel polyclonal antibody against GSTCD for diagnostic applications"*
**作者**：Zhang Y, et al.
**摘要**：本文报道了一种新型GSTCD多克隆抗体的开发与验证，通过ELISA和免疫组化证实其高特异性，并应用于COPD患者肺组织样本中GSTCD蛋白的定量分析。
(注：以上文献为示例，实际引用请以真实学术数据库检索结果为准。)
The glutathione S-transferase C-terminal domain-containing (GSTCD) protein is encoded by the GSTCD gene, located on human chromosome 4q24. Initially identified through genome-wide association studies (GWAS), GSTCD has been linked to lung function parameters, particularly forced expiratory volume (FEV1) and the FEV1/forced vital capacity (FVC) ratio, suggesting a role in respiratory health. While its exact molecular function remains unclear, GSTCD is hypothesized to interact with glutathione S-transferases (GSTs), enzymes involved in detoxification and oxidative stress response. It may also influence ciliary function in airway epithelial cells, potentially impacting obstructive lung diseases like asthma and COPD.
GSTCD antibodies are tools developed to study the protein's expression, localization, and biological mechanisms. These antibodies enable detection of GSTCD in tissues (e.g., via Western blotting, immunohistochemistry) and facilitate research into its association with pulmonary pathophysiology. Studies using GSTCD antibodies have explored its tissue-specific expression patterns, particularly in the lung, and its potential regulatory roles in gene networks affecting airway function. Despite progress, further research is needed to clarify GSTCD's precise functional pathways and its contribution to disease susceptibility, highlighting the continued relevance of GSTCD antibodies in respiratory and molecular studies.
×
