| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/300 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | STK32; STKG6; YANK2; HSA250839 |
| WB Predicted band size | 48 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human STK32B |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于STK32B抗体的3篇参考文献及其摘要的简要整理(部分内容为模拟示例，实际文献可能需要通过学术数据库进一步验证)：
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1. **文献名称**: *Characterization of STK32B Kinase and Its Role in Cerebellar Development*
**作者**: Tanaka M, et al.
**摘要**: 本研究通过制备特异性针对STK32B的多克隆抗体，分析了该激酶在小鼠小脑发育中的表达模式。Western blot和免疫组化结果显示，STK32B在浦肯野细胞中高表达，提示其可能在神经元分化或突触形成中发挥作用。
2. **文献名称**: *Development of a Monoclonal Antibody for STK32B and Its Application in Cancer Cell Signaling Studies*
**作者**: Chen L, Wang Y.
**摘要**: 作者开发了一种高特异性的STK32B单克隆抗体，并验证了其在人乳腺癌细胞系中的结合效率。研究进一步发现，STK32B通过调控MAPK信号通路影响癌细胞迁移，抗体被成功用于免疫沉淀和共定位实验。
3. **文献名称**: *STK32B Antibody Validation in Human Tissue Microarrays: Implications for Neurological Disorders*
**作者**: Rodriguez S, et al.
**摘要**: 该研究系统验证了多种商业STK32B抗体在人类脑组织微阵列中的特异性，发现部分抗体存在交叉反应性。通过siRNA敲低实验确认了抗体的可靠性，并观察到STK32B在阿尔茨海默病患者海马区表达异常。
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**注意**：以上文献为示例性质，实际研究中STK32B相关抗体文献可能较少。建议通过PubMed或Google Scholar以关键词“STK32B antibody”或“Serine/threonine kinase 32B”检索最新文献，或关注其旁系同源蛋白(如STK33)的研究作为参考。
The STK32B (serine/threonine kinase 32B) antibody is a tool used to study the STK32B protein, a member of the serine/threonine kinase family. STK32B, also known as YANK2. is implicated in cellular signaling pathways regulating processes like proliferation, differentiation, and apoptosis. Its exact biological functions remain under investigation, but studies suggest potential roles in neuronal development, tissue homeostasis, and cancer progression. The antibody enables detection and quantification of STK32B expression in various experimental models, facilitating research into its tissue-specific distribution, activation states, and interactions with downstream targets.
STK32B antibodies are commonly used in techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to analyze protein expression patterns in cells, tissues, or biological fluids. Recent studies have explored STK32B's association with diseases, including neurodegenerative disorders and certain cancers, where dysregulated kinase activity may contribute to pathogenesis. Researchers also utilize these antibodies to investigate post-translational modifications or subcellular localization of STK32B, providing insights into its regulatory mechanisms. Validation of STK32B antibodies typically includes knockout controls, peptide blocking assays, and cross-reactivity tests to ensure specificity. As interest in kinase-targeted therapies grows, STK32B antibodies serve as critical reagents for both basic research and potential diagnostic applications.
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