WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/50-1/200 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
Aliases | H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4FA; H4-16; H4C11; H4C12; H4C13; H4C14; H4C15; HIST1H4A |
WB Predicted band size | 11 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Fusion protein of human H4C1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇关于H4C1抗体的参考文献(示例为模拟生成内容,实际文献需通过数据库验证):
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1. **文献名称**: "Histone H4 acetylation dynamics determined by stable isotope labeling with amino acids in cell culture and mass spectrometry"
**作者**: Smith A, et al.
**摘要**: 本研究利用H4C1特异性抗体,结合SILAC标记和质谱技术,定量分析了HeLa细胞中组蛋白H4乙酰化修饰的动态变化,揭示了其在细胞周期进程中的调控作用。
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2. **文献名称**: "Chromatin immunoprecipitation analysis of histone H4K12 acetylation in neuronal differentiation"
**作者**: Chen L, et al.
**摘要**: 通过H4C1抗体(针对H4K12乙酰化位点)进行ChIP-seq,发现该修饰在小鼠神经干细胞分化过程中显著富集于神经元特异性基因启动子区域,提示其参与神经分化表观调控。
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3. **文献名称**: "Aberrant histone H4 modification in hepatocellular carcinoma revealed by antibody-based profiling"
**作者**: Tanaka K, et al.
**摘要**: 采用多种组蛋白抗体(包括H4C1)对肝癌组织进行免疫组化分析,发现H4K16乙酰化水平显著降低,可能与肝癌患者预后不良相关。
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注:以上内容为模拟生成,实际文献需通过PubMed或Google Scholar以关键词“H4C1 antibody”“H4 histone modification”等检索。建议结合具体研究场景筛选抗体应用(如ChIP、WB、IF等)相关的论文。
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