Rabbit Polyclonal TSSK4 Antibody

The TSSK4 (Testis-Specific Serine Kinase 4) antibody is a tool used to detect and study the TSSK4 protein, a member of the testis-specific serine/threonine kinase family. TSSK4 is predominantly expressed in the testis, particularly during spermatogenesis, and is implicated in sperm development and male fertility. Its specific molecular functions remain under investigation, but studies suggest roles in cellular processes such as chromatin remodeling, sperm maturation, and acrosome formation. The TSSK4 antibody enables researchers to localize and quantify the protein in tissue samples, aiding in explorations of its expression patterns and interactions. Commercially available antibodies are typically validated in applications like Western blotting, immunohistochemistry, and immunofluorescence. Research using TSSK4 antibodies has contributed to understanding male reproductive disorders, including idiopathic infertility, and potential contraceptive targets. Cross-reactivity with other TSSK family members (TSSK1-3. 6) is a key consideration, requiring validation via knockout controls. Recent studies also explore TSSK4's potential involvement in non-reproductive cancers, though its clinical relevance remains speculative. As a relatively understudied kinase, TSSK4 antibodies remain critical for elucidating its biological significance in gametogenesis and disease pathology.