首页 / 产品 / 抗体 / 一抗

Rabbit Polyclonal LHB Antibody

  • 中文名: LHB抗体
  • 别    名: CGB4; HH23; LSH-B; LSH-beta
货号: IPDX10997
Price: ¥1180
数量:
大包装询价

验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/50-1/200 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/5000-1/10000 Human,Mouse,Rat

产品详情

参考文献

以下是为您模拟的3篇关于LHB抗体的虚构参考文献示例(注:实际文献请通过学术数据库检索获取):

---

**1. 文献名称**: *Development of a High-Specificity Monoclonal Antibody for Human Luteinizing Hormone Beta Subunit*

**作者**: Smith A, et al.

**摘要**: 本研究报道了一种新型抗人LHB亚基单克隆抗体的开发。该抗体通过杂交瘤技术制备,在ELISA和免疫组化中显示出高亲和力与特异性,可区分LH与其他糖蛋白激素(如FSH、hCG),为生殖内分泌疾病的精准诊断提供了新工具。

---

**2. 文献名称**: *LHB Antibody-Based Blockade Therapy in Polycystic Ovary Syndrome Model Mice*

**作者**: Zhang Y, et al.

**摘要**: 通过在小鼠模型中注射抗LHB抗体,研究团队发现该抗体可有效降低异常升高的LH水平,改善卵巢多囊化症状和激素失衡。结果表明,LHB靶向抗体可能成为多囊卵巢综合征(PCOS)的潜在治疗策略。

---

**3. 文献名称**: *Cross-Species Reactivity Analysis of Anti-LHB Antibodies in Mammalian Reproduction Studies*

**作者**: Johnson R, et al.

**摘要**: 本文系统评估了不同物种(人类、大鼠、牛)LHB抗体的交叉反应性,发现部分单克隆抗体在跨物种检测中保留结合能力。该发现为生殖生物学比较研究及兽医学应用提供了重要参考依据。

---

**建议**:实际研究中请通过 **PubMed**(https://pubmed.ncbi.nlm.nih.gov/)或 **Google Scholar** 检索关键词“LHB antibody”“LH beta subunit monoclonal”等,筛选近年高被引文献。如需全文访问权限,可尝试使用科研机构订阅库或开放获取平台(如PubMed Central)。

背景信息

Luteinizing hormone (LH) is a glycoprotein hormone critical for reproductive function, composed of two subunits: α (common to TSH, FSH, and hCG) and a unique β-subunit (LHB) that confers biological specificity. Antibodies targeting LHB are essential tools in studying LH's role in regulating ovulation, testosterone synthesis, and gonadal steroidogenesis. They enable precise detection of LH in immunoassays, aiding in diagnosing conditions like infertility, polycystic ovary syndrome (PCOS), and hypogonadism. Monoclonal LHB antibodies, generated via hybridoma or recombinant technologies, offer high specificity, minimizing cross-reactivity with structurally similar hormones (e.g., hCG). Recent research explores therapeutic applications, such as blocking LH activity in hormone-dependent cancers or modulating LH receptor signaling. However, challenges remain in ensuring antibody stability and avoiding interference from isoform variants. Advances in epitope mapping and phage display libraries continue to refine LHB antibody development, enhancing their utility in both research and clinical diagnostics. Understanding LHB antibody interactions also sheds light on LH dysregulation mechanisms, informing targeted therapies for endocrine disorders.

客户数据及评论

折叠内容

大包装询价

×