| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | ANTP; HOX1; HOX1A; HOX1.1 |
| WB Predicted band size | 25 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human HOXA7 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于HOXA7抗体的参考文献示例(内容为虚构，仅供格式参考)：
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1. **文献名称**: *HOXA7 Expression in Cervical Cancer and Its Clinical Implications*
**作者**: Smith A, et al.
**摘要**: 本研究通过免疫组化(使用HOXA7特异性抗体)分析宫颈癌组织中HOXA7蛋白的表达水平，发现其高表达与肿瘤侵袭性和不良预后显著相关，提示HOXA7可能作为潜在生物标志物。
2. **文献名称**: *HOXA7 Antibody Validation for Western Blot and Immunofluorescence*
**作者**: Lee B, et al.
**摘要**: 文章系统验证了商业化HOXA7抗体的特异性，通过siRNA敲低实验和质谱分析确认其在Western blot及免疫荧光中的可靠性，为后续功能研究提供实验依据。
3. **文献名称**: *HOXA7 in Hematopoietic Differentiation: A Flow Cytometry Study*
**作者**: Chen C, et al.
**摘要**: 利用流式细胞术(基于HOXA7抗体标记)探究HOXA7在造血干细胞分化中的作用，发现其表达下调与髓系分化异常相关，可能参与白血病发生机制。
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注：以上文献为示例，实际引用需检索PubMed/Google Scholar等平台，关键词“HOXA7 antibody”、“HOXA7 immunohistochemistry”或结合特定疾病名称(如癌症类型)。
The HOXA7 antibody is a valuable tool in studying the HOX family of transcription factors, which play pivotal roles in embryonic development and cellular differentiation. HOX genes, organized into four clusters (A-D), regulate body patterning along the anterior-posterior axis. HOXA7. located on chromosome 7p15.2. encodes a DNA-binding protein critical for limb development, organogenesis, and hematopoietic stem cell regulation. Dysregulation of HOXA7 has been implicated in cancers (e.g., leukemia, breast cancer) and developmental disorders.
HOXA7 antibodies enable detection and localization of the HOXA7 protein in tissues and cell lines through techniques like Western blot, immunohistochemistry, and immunofluorescence. These antibodies aid in exploring HOXA7's expression patterns, interaction partners, and downstream targets. Commercial HOXA7 antibodies are typically raised against specific epitopes, often in rabbit or mouse hosts, with validation across multiple applications.
Recent studies highlight HOXA7's dual roles as both oncogene and tumor suppressor depending on context. Its overexpression in some malignancies correlates with metastasis and poor prognosis, while reduced expression is linked to developmental defects. Researchers also investigate HOXA7 in epigenetic regulation and its crosstalk with signaling pathways like Wnt and TGF-β. The antibody's utility extends to developmental biology, cancer research, and regenerative medicine, making it essential for decoding HOXA7's multifaceted functions.
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