| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | STK32; STKG6; YANK2; HSA250839 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human STK32B |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于STK32B抗体的模拟参考文献(实际文献需通过学术数据库查询)：
1. **文献名称**：STK32B Kinase Activity in Cerebellar Development
**作者**：Smith A, et al.
**摘要**：研究STK32B在小脑发育中的功能，通过特异性抗体检测其蛋白表达水平，发现STK32B在小脑颗粒细胞分化中调控细胞周期进程。
2. **文献名称**：A Novel STK32B Antibody for Immunohistochemical Analysis
**作者**：Li Y, et al.
**摘要**：开发了一种高特异性STK32B单克隆抗体，验证其在人组织样本中的可靠性，并发现STK32B在多种肿瘤组织中异常高表达。
3. **文献名称**：STK32B Interaction Network Revealed by Co-Immunoprecipitation
**作者**：Garcia R, et al.
**摘要**：利用STK32B抗体进行免疫共沉淀实验，鉴定了其与细胞骨架蛋白的相互作用，提示其在细胞极性建立中的作用。
4. **文献名称**：STK32B Phosphorylation and Neuronal Apoptosis
**作者**：Wang X, et al.
**摘要**：通过抗体检测STK32B磷酸化状态，证明其在氧化应激诱导的神经元凋亡中通过MAPK通路发挥保护作用。
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**注意**：以上内容为模拟生成，实际文献请通过PubMed、Web of Science或Google Scholar等平台，以“STK32B antibody”、“STK32B kinase”等关键词检索。
The STK32B (serine/threonine kinase 32B) antibody is a tool used to study the STK32B protein, a member of the YANK (Yet Another Kinase) family. STK32B, also known as YANK2. is a relatively understudied kinase implicated in cellular signaling pathways, though its precise biological roles remain unclear. It shares structural homology with other kinases, featuring a conserved catalytic domain for phosphorylating serine/threonine residues. Research suggests potential involvement in cell proliferation, differentiation, or stress responses, with expression detected in tissues like the brain, testes, and kidneys.
Antibodies targeting STK32B are typically developed in hosts like rabbits or mice using immunogenic peptides or recombinant protein fragments. These antibodies enable detection and localization of STK32B via techniques such as Western blotting, immunohistochemistry, or immunofluorescence. They are critical for exploring STK32B’s expression patterns, interactions, and regulatory mechanisms in both normal and disease contexts.
Interest in STK32B has grown due to possible links to neurological disorders and cancers, where kinase dysregulation is common. However, limited studies highlight the need for further validation of its functions. Commercial STK32B antibodies often undergo specificity testing (e.g., knockout controls) to ensure reliability. Researchers prioritize antibodies with high affinity and minimal cross-reactivity to related kinases. As STK32B’s roles are elucidated, its antibody remains vital for unraveling its contributions to cellular processes and pathologies.
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