WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/20-1/100 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
Aliases | FIM; MYM; RAMP; SCLL; ZNF198 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human ZMYM2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于ZMYM2抗体的参考文献示例(注:文献为示例性内容,建议通过学术数据库核实真实文献):
1. **文献名称**:*ZMYM2 interacts with the NuRD complex to regulate transcriptional repression and chromatin compaction*
**作者**:Hakimi MA, et al.
**摘要**:本研究利用ZMYM2特异性抗体进行免疫共沉淀(Co-IP)和染色质免疫沉淀(ChIP-seq),揭示ZMYM2与NuRD复合体相互作用,参与基因沉默和染色质结构调控,提示其在表观遗传修饰中的关键作用。
2. **文献名称**:*Functional characterization of ZMYM2 in maintaining telomeric heterochromatin integrity*
**作者**:Shi Y, et al.
**摘要**:通过CRISPR/Cas9敲除结合ZMYM2抗体的免疫荧光分析,发现ZMYM2对端粒异染色质的稳定性至关重要,抗体验证显示其在细胞核内与端粒区域共定位,影响端粒长度调控。
3. **文献名称**:*ZMYM2 is a novel biomarker for aggressive prostate cancer identified by antibody-based proteomic screening*
**作者**:Liu X, et al.
**摘要**:采用ZMYM2抗体对前列腺癌组织进行免疫组化(IHC)分析,发现ZMYM2高表达与肿瘤转移和不良预后显著相关,提示其作为潜在临床标志物的价值。
4. **文献名称**:*Structural insights into ZMYM2-FGFR1 oncogenic fusion proteins using epitope-specific antibodies*
**作者**:Park J, et al.
**摘要**:针对ZMYM2-FGFR1融合蛋白的特异性抗体被开发并用于Western blot和免疫沉淀,证实其在血液系统肿瘤中异常激活MAPK信号通路的机制。
**提示**:以上为模拟示例,实际文献请通过PubMed、Google Scholar等平台以关键词“ZMYM2 antibody”或“ZMYM2 immunohistochemistry”检索。
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