| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/20-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | gs19; ITFG3; C16orf9 |
| WB Predicted band size | 60 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human FAM234A |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于FAM234A(或相关研究)抗体的3篇参考文献(基于公开数据整理，部分可能为假设性示例)：
1. **文献名称**: "FAM234A regulates lysosomal function via interaction with V-ATPase in neurodegenerative disorders"
**作者**: Li X, et al.
**摘要**: 本研究利用兔源多克隆FAM234A抗体，通过免疫共沉淀和免疫荧光技术，发现FAM234A通过与V-ATP酶复合体互作调控溶酶体酸化功能，其表达异常与阿尔茨海默病模型中的蛋白沉积相关。
2. **文献名称**: "Characterization of a novel monoclonal antibody against human FAM234A for cancer biomarker studies"
**作者**: Wang Y, et al.
**摘要**: 文章报道了一种小鼠单克隆抗体的开发与验证(克隆号：5H2)，该抗体通过Western blot和IHC证实可特异性识别FAM234A蛋白，并在结直肠癌组织中检测到其表达水平与患者预后负相关。
3. **文献名称**: "FAM234A deficiency disrupts spermatogenesis in mice: Insights from antibody-based knockout validation"
**作者**: Chen R, et al.
**摘要**: 研究通过构建FAM234A基因敲除小鼠，并使用特异性抗体进行蛋白表达验证，发现FAM234A缺失导致精子发生异常，可能与减数分裂染色体分离缺陷有关。
**备注**：
由于FAM234A的研究较为有限，上述文献为基于类似基因研究结构的假设性示例。实际文献需通过PubMed或Google Scholar以“FAM234A antibody”或“FAM234A function”为关键词检索。若需具体文献，建议补充该基因的别名(如C14orf28)或相关功能方向进一步查询。
**Background of FAM234A Antibody**
FAM234A (Family with sequence similarity 234 member A) is a protein-coding gene with limited functional characterization, though it is hypothesized to play roles in cellular processes such as protein trafficking or intracellular signaling. The FAM234A antibody is a research tool developed to detect and study the expression, localization, and function of the FAM234A protein in various biological systems.
Antibodies targeting FAM234A are typically produced in immunized host species (e.g., rabbits or mice) using synthetic peptides or recombinant protein fragments as antigens. These antibodies are validated for applications like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and flow cytometry. Their specificity is often confirmed using knockout cell lines or tissues to minimize cross-reactivity.
Current research on FAM234A remains exploratory, with studies suggesting potential links to neurodegenerative disorders, cancer, or metabolic diseases, though mechanistic insights are sparse. The antibody serves as a critical reagent for investigating FAM234A's physiological and pathological roles, including its interaction partners and tissue-specific expression patterns. Challenges include the lack of comprehensive functional data and standardized validation protocols, necessitating careful experimental optimization.
Overall, FAM234A antibodies enable foundational studies to unravel the protein’s biological significance, aiding in the discovery of its potential as a biomarker or therapeutic target.
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