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产品描述：人低密度脂蛋白受体相关蛋白1(LRP-1)酶联免疫试剂盒为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的LRP1含量。LRP1是一种细胞表面受体，在人体多个组织广泛表达。其作为内吞受体，可参与清除细胞外多种配体。研究发现，它参与细胞内信号传导，与细胞增殖、迁移等密切相关，在神经退行性疾病、癌症等疾病的发生发展中起作用。试剂盒检测范围为0.625 ng/mL-40 ng/mL，科研人员可通过定量分析不同生理或病理条件下生物样本中LRP-1的浓度变化，适用于心血管疾病机制研究、神经退行性疾病模型验证、药物靶点筛选及代谢相关信号通路探索等科研领域；支持常规实验室开展稳定、高效的ELISA检测。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
别名：A2MR ELISA Kit; Alpha 2 macroglobulin receptor ELISA Kit; alpha 2MR ELISA Kit; Alpha-2-macroglobulin receptor ELISA Kit; APOER ELISA Kit; Apolipoprotein E receptor ELISA Kit; APR ELISA Kit; CD 91 ELISA Kit; CD91 ELISA Kit; CD91 antigen ELISA Kit; IGFBP3R ELISA Kit; LDL receptor related protein 1 ELISA Kit; Low density lipoprotein receptor related protein 1 ELISA Kit; Low density lipoprotein related protein 1 ELISA Kit; Low-density lipoprotein receptor-related protein 1 intracellular domain ELISA Kit; LRP 1 ELISA Kit; LRP 515 ELISA Kit; LRP 85 ELISA Kit; LRP ELISA Kit; LRP ICD ELISA Kit; LRP-1 ELISA Kit; LRP-515 ELISA Kit; LRP-85 ELISA Kit; Lrp1 ELISA Kit; LRP1 protein ELISA Kit; LRP1_HUMAN ELISA Kit; LRP1A ELISA Kit; LRP515 ELISA Kit; LRP85 ELISA Kit; LRPICD ELISA Kit; MGC88725 ELISA Kit; Prolow density lipoprotein receptor related protein 1 ELISA Kit; TbetaR V/LRP 1/IGFBP 3 receptor ELISA Kit; TbetaRV/LRP1/IGFBP3 receptor ELISA Kit; TGFBR 5 ELISA Kit; TGFBR5 ELISA Kit; Type V tgf beta receptor ELISA Kit
缩写：LRP1
Uniprot No.：Q07954
种属：Homo sapiens (Human)
样本类型：serum, plasma, tissue homogenates
检测范围：0.625 ng/mL-40 ng/mL
灵敏度：0.156 ng/mL
反应时间：1-5h
样本体积：50-100ul
检测波长：450 nm
研究领域：Signal Transduction
测定原理：quantitative
测定方法：Sandwich
精密度：
| Intra-assay Precision (Precision within an assay): CV%<8% | ||||||
| Three samples of known concentration were tested twenty times on one plate to assess. | ||||||
| Inter-assay Precision (Precision between assays): CV%<10% | ||||||
| Three samples of known concentration were tested in twenty assays to assess. | ||||||
线性度：
| To assess the linearity of the assay, samples were spiked with high concentrations of human LRP-1 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. | ||||||
| Sample | Serum(n=4) | |||||
| 1:1 | Average % | 93 | ||||
| Range % | 88-97 | |||||
| 1:2 | Average % | 84 | ||||
| Range % | 80-89 | |||||
| 1:4 | Average % | 102 | ||||
| Range % | 96-108 | |||||
| 1:8 | Average % | 97 | ||||
| Range % | 91-102 | |||||
回收率：
| The recovery of human LRP-1 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. | ||||||
| Sample Type | Average % Recovery | Range | ||||
| Serum (n=5) | 86 | 82-94 | ||||
| EDTA plasma (n=4) | 99 | 92-107 | ||||
标准曲线：
| These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. | ||||||
| ng/mlOD1OD2AverageCorrected402.4552.3542.4052.262201.6281.5271.5781.435100.9760.9550.9660.82350.5660.5770.5720.4292.50.3710.3820.3770.2341.250.2670.2780.2730.1300.6250.2100.2160.2130.07000.1420.1430.143 | ||||||
货期：3-5 working days
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