Cat: IPD-X38458

Recombinant Mouse ITGb6 Protein,His

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关键信息

  • 基因名

    ITGb6

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    ITG-B6

  • 种属

    Mouse

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9Z0T9

  • 表达区间

    Tyr131~Thr619

  • 分子量

    57kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

ITGb6, or integrin beta-6, is a member of the integrin family of cell adhesion molecules, playing a crucial role in various biological processes, including cell-matrix adhesion, migration, and signaling. It is primarily expressed in epithelial cells and is implicated in crucial physiological functions, such as wound healing and tissue repair. In recent years, research has highlighted the significance of ITGb6 in various pathological conditions, particularly in cancer, where its overexpression is linked to enhanced tumor growth, metastasis, and poor prognosis. The investigation of ITGb6 as a target for therapeutic intervention has gained momentum, with scientists looking to understand its mechanism of action at the molecular level. Recombining ITGb6 protein has emerged as a key strategy for studying its structure and function, facilitating the exploration of its potential as a biomarker for cancer diagnosis and prognosis. Additionally, engineered ITGb6 proteins can be employed in drug delivery systems and tissue engineering applications, which may ultimately lead to novel therapeutic strategies for cancer and other diseases. This ongoing research is crucial for establishing ITGb6 not only as a therapeutic target but also as a critical player in the understanding of integrin-mediated cellular processes. As the knowledge surrounding ITGb6 expands, so too does the potential for innovative treatments aimed at diseases characterized by dysregulated cell adhesion and migration, highlighting the importance of recombinant ITGb6 protein studies in advancing biomedical research.

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