关键信息
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基因名
MRPL19
- 应用
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别名
39S ribosomal protein L15, mitochondrial ;L15mt ;MRP-L15
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P49406
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表达区间
1-292aa
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分子量
60.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MRPL19, or mitochondrial ribosomal protein L19, is a crucial component of the mitochondrial ribosome, playing a vital role in protein synthesis within mitochondria. Mitochondria are essential organelles responsible for energy production, and their proper function is critical for cellular metabolism and overall health. Research on MRPL19 is particularly significant due to its implications in mitochondrial diseases and apoptosis, as well as its involvement in various cellular processes. Deficiencies or mutations in MRPL19 can lead to mitochondrial dysfunction, contributing to a range of metabolic disorders and age-related diseases. Recent studies have emphasized the importance of MRPL19 in maintaining mitochondrial integrity and function, as well as its potential as a biomarker for specific disease states. Understanding the structure, function, and regulatory mechanisms of MRPL19 is essential for developing therapeutic strategies aimed at ameliorating mitochondrial dysfunction-related conditions. Given the increased prevalence of mitochondrial diseases and their complex nature, ongoing research into MRPL19 and its interactions within the mitochondrial ribosome could provide novel insights into the fundamental mechanisms of mitochondrial biology and disease. As such, MRPL19 represents a promising target for further investigation, potentially leading to advancements in mitochondrial therapeutics and enhancing our understanding of cellular energy dynamics.
