| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Protein FAM199X, FAM199X, CXorf39 |
| Entrez GeneID | 139231 |
| WB Predicted band size | 42.8kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This CXorf39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human CXorf39. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是几篇关于CXorf39抗体的示例参考文献(注：以下内容为虚构示例，实际文献请通过PubMed或专业学术数据库查询)：
1. **文献名称**: "Characterization of CXorf39 Antibody in Prostate Cancer Tissues"
**作者**: Smith A, et al.
**摘要**: 本研究利用兔源多克隆CXorf39抗体，通过免疫组化技术分析前列腺癌组织中CXorf39蛋白的异常表达，发现其与肿瘤侵袭性呈正相关，提示其作为潜在生物标志物的可能性。
2. **文献名称**: "Development of a Monoclonal Antibody Targeting CXorf39 for Functional Studies"
**作者**: Chen L, et al.
**摘要**: 报道了一种新型小鼠单克隆抗体的制备与验证，该抗体特异性识别CXorf39蛋白的C端结构域，成功用于Western blot和免疫荧光实验，揭示了CXorf39在细胞核内的定位特征。
3. **文献名称**: "CXorf39 Expression in Female-Specific Cancers: Insights from Antibody-Based Profiling"
**作者**: González R, et al.
**摘要**: 通过商业化CXorf39抗体对卵巢癌和乳腺癌组织芯片进行筛查，发现CXorf39在激素受体阳性亚型中显著高表达，可能与雌激素信号通路存在关联。
4. **文献名称**: "The Role of CXorf39 in Immune Regulation: Evidence from Knockout Models and Antibody Blockade"
**作者**: Tanaka K, et al.
**摘要**: 结合CXorf39基因敲除小鼠模型及中和抗体实验，证明CXorf39通过调控T细胞活化影响自身免疫性疾病进程，为治疗靶点开发提供依据。
**注意**：以上文献为示例性质，实际研究需通过学术数据库(如PubMed、Web of Science)以“CXorf39 antibody”或“CXorf39 protein”为关键词检索。若需具体文献协助，可提供更多背景信息进一步筛选。
The CXorf39 antibody targets the protein encoded by the CXorf39 (chromosome X open reading frame 39) gene, located on the X chromosome. This gene, also known as X-Linked Lymphocyte-Regulated 3A (XLR3A), encodes a poorly characterized protein believed to play roles in immune regulation and cellular processes. CXorf39 is expressed in various tissues, including immune cells, and has been implicated in cancer biology, particularly in malignancies linked to X chromosome alterations, such as certain lymphomas and solid tumors. Its exact molecular function remains unclear, but studies suggest potential involvement in chromatin remodeling, transcriptional regulation, or cell cycle control due to structural features like nuclear localization signals.
CXorf39 antibodies are primarily used in research to detect protein expression via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). These tools help explore CXorf39's tissue distribution, subcellular localization, and potential association with disease mechanisms. Commercial antibodies are often raised in rabbits or mice using synthetic peptides or recombinant protein fragments. Validation data, including specificity checks using knockout controls, are critical due to occasional cross-reactivity concerns. Recent interest in CXorf39 stems from its possible role as a tumor-associated antigen or biomarker, though further studies are needed to clarify its biological significance and therapeutic potential.
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