关键信息
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基因名
MS4A8B
- 应用
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别名
MS4A8; 4SPAN4; MS4A8B; Membrane-spanning 4-domains subfamily A member 8; Four-span transmembrane protein 4; Membrane-spanning 4-domains subfamily A member 8B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BY19
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表达区间
1-250 aa
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氨基酸序列
MNSMTSAVPVANSVLVVAPHNGYPVTPGIMSHVPLYPNSQPQVHLVPGNPPSLVSNVNGQ PVQKALKEGKTLGAIQIIIGLAHIGLGSIMATVLVGEYLSISFYGGFPFWGGLWFIISGS LSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPHPYAYPDYYPYAWGVNP GMAISGVLLVFCLLEFGIACASSHFGCQLVCCQSSNVSVIYPNIYAANPVITPEPVTSPP SYSSEIQANK
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分子量
26.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MS4A8B, a member of the Membrane-Spanning 4-Domains Subfamily A (MS4A) family, has garnered attention in immunological research due to its potential role in regulating immune responses. This protein is primarily expressed in immune cells, including B cells and T cells, suggesting its involvement in adaptive immunity. Studies have indicated that MS4A8B may participate in cell signaling pathways that influence the activation and proliferation of lymphocytes. Furthermore, genetic variation in the MS4A gene cluster has been associated with several autoimmune diseases, including multiple sclerosis and systemic lupus erythematosus. This suggests a potential link between MS4A8B and the pathogenesis of these conditions. Understanding the structure and function of the MS4A8B recombinant protein could provide insights into its precise role in immune regulation and its implications for disease. Recent advancements in recombinant protein technology have enabled the production and characterization of MS4A8B, allowing for detailed studies of its molecular interactions and functional properties. This research could pave the way for novel therapeutic strategies targeting MS4A8B-related pathways in autoimmune diseases, contributing to improved patient outcomes and advancements in immunology. Thus, investigating MS4A8B not only enhances our understanding of its biological functions but also holds promise for future clinical applications.
