| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FAM9C |
| Uniprot No | Q8IZT9 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-166aa |
| 氨基酸序列 | MAAKDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGEKEEQIKIFQEQQKRWQQDGKGTERD |
| 分子量 | 45.6 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是假设的3篇关于重组人FAM9C蛋白的参考文献示例(实际文献可能存在差异，建议通过学术数据库验证)：
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1. **文献名称**：*"Expression and Functional Analysis of Recombinant Human FAM9C in Spermatogenesis"*
**作者**：Zhang, L. et al. (2018)
**摘要**：研究通过大肠杆菌系统成功表达重组人FAM9C蛋白，并发现其在体外模型中促进精子形成相关基因的转录调控，提示FAM9C可能参与男性生殖细胞发育。
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2. **文献名称**：*"Structural Characterization of FAM9C and Its Role in X-Chromosome Inactivation"*
**作者**：Wang, Y. et al. (2020)
**摘要**：利用重组FAM9C蛋白进行晶体结构解析，揭示其与XIST RNA的相互作用机制，提出FAM9C可能通过表观遗传调控参与X染色体失活过程。
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3. **文献名称**：*"Recombinant FAM9C Protein Attenuates Oxidative Stress-Induced Apoptosis in Ovarian Granulosa Cells"*
**作者**：Chen, H. et al. (2021)
**摘要**：在卵巢颗粒细胞中验证重组FAM9C的抗凋亡功能，证实其通过激活PI3K/AKT信号通路减轻氧化应激损伤，为生殖疾病治疗提供潜在靶点。
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如需真实文献，建议检索 **PubMed** 或 **Google Scholar**，关键词："recombinant FAM9C"、"human FAM9C protein function"。
**Background of Recombinant Human FAM9C Protein**
FAM9C (family with sequence similarity 9 member C) is a protein-coding gene located on the X chromosome (Xp22.2). It belongs to the FAM9 family, which includes FAM9A, FAM9B, and FAM9C. These genes exhibit testis-specific or testis-predominant expression patterns, suggesting potential roles in spermatogenesis or male reproductive functions. While the precise biological role of FAM9C remains unclear, it shares structural homology with other FAM9 proteins, which are hypothesized to participate in chromatin organization, transcriptional regulation, or gamete development.
Recombinant human FAM9C protein is engineered in vitro using expression systems (e.g., *E. coli*, mammalian cells*) to enable functional studies. Its production allows researchers to explore interactions with other biomolecules, cellular localization, and potential involvement in fertility-related pathways. Current studies are limited, but FAM9C’s X-chromosomal linkage and expression in reproductive tissues hint at roles in sex chromosome biology or disorders like male infertility.
Research on FAM9C is still nascent, with challenges including the lack of specific antibodies and functional assays. However, recombinant protein tools may help unravel its molecular mechanisms, offering insights into its physiological significance and possible applications in reproductive health or contraceptive development. Further investigations, such as knockout models or interactome analyses, are critical to define FAM9C’s contribution to cellular processes and human health.
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