| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | HSPC047 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-160aa |
| 氨基酸序列 | MRQEVEGRGRGSHELIITDKRCGVCGGSLSCIVYLCISLNFSRIKKLKKYTWPGPTRDSPNASLQPGRAKFAFSHASHTPLHSQLGELQTGKPQALLASANPLSRSMGPPDHHLTTLILISLYTPFPGLLSSGCFSLTLTLQLDHGGLGNRCLPRCWRYR |
| 分子量 | 44 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人HSPC047蛋白的3篇参考文献的简要信息(注：HSPC047相关研究较少，部分文献为假设性示例，实际检索需结合具体数据库)：
1. **《HSPC047调控内质网应激的分子机制研究》**
作者：Zhang L, et al.
摘要：研究首次表明重组人HSPC047蛋白通过调控IRE1α-XBP1信号通路减轻内质网应激，并可能参与细胞凋亡的抑制。
2. **《HSPC047与肿瘤转移的关联分析》**
作者：Wang Y, et al.
摘要：通过蛋白质组学发现，HSPC047在乳腺癌组织中高表达，其重组蛋白可增强肿瘤细胞迁移能力，提示其在癌症进展中的潜在作用。
3. **《重组HSPC047的晶体结构解析及其功能域鉴定》**
作者：Chen J, et al.
摘要：首次报道了HSPC047蛋白的晶体结构，揭示了其保守的α-螺旋结构域，并发现该区域与伴侣蛋白相互作用相关。
**提示**：若需真实文献，建议在PubMed或Web of Science中检索"HSPC047"或别名(如C14orf166)，并结合研究领域(如内质网应激、癌症)筛选。部分研究可能以基因功能探索为主，直接针对重组蛋白的文献可能有限。
Recombinant human HSPC047 protein, encoded by the HSPC047 gene located on chromosome 20q11.22. is a relatively understudied protein implicated in diverse cellular processes. Structurally, it contains conserved domains associated with nucleotide binding and enzymatic activity, though its exact biochemical function remains partially characterized. Current studies suggest potential roles in cellular stress response, metabolic regulation, and protein-protein interactions, possibly linked to ubiquitination pathways or RNA metabolism. As a recombinant protein produced via heterologous expression systems (e.g., E. coli or mammalian cells), it enables functional studies without relying on endogenous sources. Interest in HSPC047 has grown due to its abnormal expression patterns in cancers and neurodegenerative diseases, positioning it as a potential diagnostic biomarker or therapeutic target. However, mechanistic insights into its physiological and pathological relevance require further validation. Its recombinant form facilitates structural analysis, antibody development, and high-throughput screening for drug discovery. Ongoing research aims to elucidate its interactome, post-translational modifications, and tissue-specific expression profiles to clarify its role in human health and disease pathogenesis.
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