关键信息
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基因名
UBAP1
- 应用
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别名
UBAP1；Ubiquitin-associated Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NZ09
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表达区间
1-502aa
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氨基酸序列
MASKKLGADF HGTFSYLDDV PFKTGDKFKT PAKVGLPIGF SLPDCLQVVR EVQYDFSLEK KTIEWAEEIK KIEEAEREAE CKIAEAEAKV NSKSGPEGDS KMSFSKTHST ATMPPPINPI LASLQHNSIL TPTRVSSSAT KQKVLSPPHI KADFNLADFE CEEDPFDNLE LKTIDEKEEL RNILVGTTGP IMAQLLDNNL PRGGSGSVLQ DEEVLASLER ATLDFKPLHK PNGFITLPQL GNCEKMSLSS KVSLPPIPAV SNIKSLSFPK LDSDDSNQKT AKLASTFHST SCLRNGTFQN SLKPSTQSSA SELNGHHTLG LSALNLDSGT EMPALTSSQM PSLSVLSVCT EESSPPNTGP TVTPPNFSVS QVPNMPSCPQ AYSELQMLSP SERQCVETVV NMGYSYECVL RAMKKKGENI EQILDYLFAH GQLCEKGFDP LLVEEALEMH QCSEEKMMEF LQLMSKFKEM GFELKDIKEV LLLHNNDQDN ALEDLMARAG AS
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
UBAP1 (Ubiquitin-Associated Protein 1) is a protein that plays a crucial role in various cellular processes, including protein homeostasis, stress response, and cell signaling. Its involvement in ubiquitin-mediated protein degradation highlights its significance in regulating cellular functions by influencing the turnover of specific proteins. Recent studies have pointed to a potential link between UBAP1 and several diseases, particularly those related to neurodegeneration and cancer. Research indicates that alterations in UBAP1 expression or function may disrupt normal cellular pathways, leading to pathological conditions. Consequently, the study of recombinant UBAP1 protein has gained traction as a promising avenue for understanding its molecular mechanisms and exploring its potential as a therapeutic target. By expressing UBAP1 in a recombinant system, researchers aim to investigate its structural properties, interaction with other proteins, and role in ubiquitin signaling pathways. This research is critical as it not only provides insights into the fundamental biology of UBAP1 but also opens up possibilities for developing novel interventions for diseases associated with its dysfunction.
