关键信息
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基因名
PDGF-CC
- 应用
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别名
PDGF-C; SCDGF; VEGF-E; Fallotein; Spinal cord-derived growth factor; Platelet-derived growth factor C, latent form; Platelet-derived growth factor C, receptor-binding form
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q8CI19
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表达区间
Glu23~Gly345
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蛋白长度
Partial
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分子量
40kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Platelet-Derived Growth Factor CC (PDGF-CC) is a member of the PDGF family, which plays a crucial role in various biological processes, including cell proliferation, survival, and migration. PDGF-CC has garnered significant research interest due to its distinct structural properties and its involvement in several pathological conditions, such as fibrosis, cancer, and vascular diseases. Unlike other PDGF isoforms, PDGF-CC is uniquely characterized by its ability to activate the PDGF receptor through dimerization, leading to the stimulation of downstream signaling pathways. Research has shown that PDGF-CC is upregulated in response to tissue injury and contributes to the pathological remodeling of tissues, making it a potential therapeutic target for conditions involving abnormal tissue repair and inflammation. Recombinant PDGF-CC has been developed to further understand its biological functions and therapeutic possibilities. Studies are ongoing to elucidate the molecular mechanisms governing PDGF-CC signaling and its role in disease processes, highlighting its potential applications in regenerative medicine and targeted therapies. Overall, the investigation of PDGF-CC not only contributes to the fundamental understanding of growth factor biology but also opens avenues for novel treatment strategies in various diseases characterized by dysregulated cell and tissue dynamics.
